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NCT06600490
Nationwide Utilization of Danish Government Electronic Letter System for Confirming the Effectiveness of Behavioral Nudges in Increasing InFLUenza Vaccine Uptake Among Adults With Chronic Disease
NA trial testing Behavioral Economic Principles in Influenza in 308,978 participants. Completed in 31 May 2025.
1 January 2025
Quick facts
| Lead sponsor | Tor Biering-Sørensen |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | other |
| Enrollment | 308,978 |
| Start date | 1 October 2024 |
| Primary completion | 1 January 2025 |
| Estimated completion | 31 May 2025 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Behavioral Economic Principles
Conditions studied
- Influenza — all drugs for Influenza →
- Behavior and Behavior Mechanisms — all drugs for Behavior and Behavior Mechanisms →
Sponsor
Tor Biering-Sørensen — full company profile →
Who can join
Adults 18 to 64, any sex, with Influenza or Behavior and Behavior Mechanisms. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In randomized clinical trials and observational studies, influenza vaccination has been shown to be effective in reducing influenza-related illness, hospitalizations, cardiovascular events, and mortality in select populations. However, the real-world effectiveness of influenza vaccination is limited by its uptake. Conducted during the 2023/2024 influenza season, the first NUDGE-FLU-CHRONIC trial demonstrated the effectiveness of behavioral nudging letters in increasing influenza vaccination rates among adults aged 18-64 years with chronic diseases in Denmark. This present study will once again investigate whether digital behavioral nudges delivered via the official, mandatory Danish electronic letter system can increase influenza vaccine uptake among adults aged 18-64 years with chronic diseases including whether the effectiveness of the previously successful strategies can be confirmed during a subsequent influenza season.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Digital Nudges to Increase Influenza Vaccination in Patients with Chronic Diseases.
Johansen ND, Vaduganathan M, Bhatt AS, Modin D, et al · · 2026 · cited 1× · PMID 41213006 · DOI 10.1056/evidoa2500265
Verify or expand the search:
- PubMed search for NCT06600490
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Behavioral Economic Principles
Trials testing the same drug.
- NCT06030739 — Nationwide Utilization of Danish Government Electronic Letter System for Increasing InFLUenza Vaccine Uptake Among Adult · NA · completed
- NCT06030726 — Nationwide Utilization of Danish Government Electronic Letter System for Confirming the Effectiveness of Behavioral Nudg · NA · completed
- NCT05542004 — Nationwide Utilization of Danish Government Electronic Letter System for Increasing InFLUenza Vaccine Uptake · NA · completed
Other recruiting trials for Influenza
Currently open trials in the same condition.
- NCT07215858 — BPL-1357 Against H1N1 Influenza Virus Challenge · Phase 2 · recruiting
- NCT07496450 — A Study of mRNA-1018-H5 Pandemic Influenza Vaccine in Healthy Adults · Phase 3 · recruiting
- NCT07302256 — A Clinical Trial of Influenza Virus Split Vaccine for Individuals Aged 60 Years and Above · Phase 1 · recruiting
- NCT07431840 — Immune Defense Protein Impact On Respiratory Immune Outcomes · NA · recruiting
- NCT07485855 — Influenza Vaccination Strategy for Patients With Hematologic Malignancy · Phase 3 · recruiting
Other Tor Biering-Sørensen trials
Trials by the same sponsor.
- NCT06952140 — Hemodynamic Effects of Ketone Esters in Patients With Sepsis Induced Cardiomyopathy · NA · not yet recruiting
- NCT06694727 — A Danish Pragmatic Randomized Trial of Nutritional Supplements in Heart Failure · Phase 3 · recruiting
- NCT06506812 — Pooled Analysis of Methodologically Harmonized Pragmatic Randomized Trials of High-Dose vs. Standard-Dose Influenza Vacc · Phase 4 · completed
- NCT06685237 — Copenhagen Heart Failure With Preserved Ejection Fraction · recruiting
- NCT06856772 — Randomized Comparison of Morning Versus Bedtime Administration of Statins: A Cardiovascular Circadian Chronotherapy (C3) · Phase 4 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06600490 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Tor Biering-Sørensen
- Last refreshed: 12 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06600490.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing