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NCT06590623: Acute_Ketone
The Effect of Acute Exogenous Oral Ketone Supplementation on Immune Cells Function and Immune Cells Histone Β-hydroxybutyrylation
NA trial testing Ketone Monoester (KE) in Ketosis, Metabolic in 12 participants. Currently enrolling.
1 June 2025
Quick facts
| Lead sponsor | University of British Columbia |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 12 |
| Start date | 1 October 2024 |
| Primary completion | 1 June 2025 |
| Estimated completion | 1 June 2025 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Ketone Monoester (KE) — full drug profile →
Conditions studied
- Ketosis, Metabolic — all drugs for Ketosis, Metabolic →
- Immune Functions — all drugs for Immune Functions →
- Histone Deacetylase (HDAC) Activity — all drugs for Histone Deacetylase (HDAC) Activity →
Sponsor
University of British Columbia
Who can join
19 and older, any sex, with Ketosis, Metabolic or Immune Functions. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To conduct a single-arm pilot study to determine how acute ingestion of an exogenous ketone monoester supplement alters the histone lysine β-hydroxybutyrylation and immune function in healthy human monocytes and lymphocytes.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06590623
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Ketone Monoester (KE)
Trials testing the same drug.
- NCT07527156 — Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure · Phase 4 · recruiting
- NCT06715748 — Effects of Exogenous Ketones on Acute Changes and Recovery of the Heart Muscle After Intense Exercise. · Phase 4 · recruiting
- NCT06108076 — Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes · EARLY_PHASE1 · recruiting
Other University of British Columbia trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06590623 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of British Columbia
- Last refreshed: 7 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06590623.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing