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NCT06589492
Comparison of Serum SIRT-1 and MMP-9 Levels of Patients With Bronchiectasis and Healthy Controls
NA trial testing Measurement of MMP-9 and SIRT-1 levels in blood serum in Bronchiectasis Adult in 60 participants. Completed in 2 September 2022.
2 September 2022
Quick facts
| Lead sponsor | Cumhuriyet University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | health services research |
| Enrollment | 60 |
| Start date | 2 November 2020 |
| Primary completion | 2 September 2022 |
| Estimated completion | 2 September 2022 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Measurement of MMP-9 and SIRT-1 levels in blood serum
Conditions studied
- Bronchiectasis Adult — all drugs for Bronchiectasis Adult →
Sponsor
Cumhuriyet University
Who can join
Eligibility, any sex, with Bronchiectasis Adult. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this a cross-sectinol study is to measure the levels of MMP-9 and SIRT-1 levels in patients with bronchiectasis and healthy controls. The aim is to compare the serum levels of these molecules between patients and controls. * Is the MMP-9 level increasing or decreasing? * Is the SIRT-1 level increasing or decreasing in patients? * Is the disease related to age and gender? Participants will only have one 5 ml blood sample drawn when they visit the chest illness clinic. Molecule levels will be measured in this blood's serum. The patient group participants will be scanned once with high-resolution chest CT. Apart from this, comparisons will be made using the age and gender information of the participants.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A cross-sectional study on the comparison of serum SIRT-1 and MMP-9 levels of patients with bronchiectasis and healthy controls.
Bakir D, Bedir MD, Ozbek DU, Seyfikli Z. · · 2025 · PMID 40290232 · DOI 10.12669/pjms.41.4.10877
Verify or expand the search:
- PubMed search for NCT06589492
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06589492 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cumhuriyet University
- Last refreshed: 19 September 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06589492.
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