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NCT06589453: D-NAM
Evaluation of Nasal Elevator Versus Grayson's Nasal Stent with D-NAM Appliance on Nasolabial Esthetics in Bilateral Cleft Lip and Palate Infants
Phase 1 trial testing Nasal elevator with digital nasoalveolar molding in bilateral cleft lip and palate infants in Cleft Lip and Cleft Palate in 20 participants. Not yet recruiting.
30 March 2026
Quick facts
| Lead sponsor | Cairo University |
|---|---|
| Phase | Phase 1 |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 1 November 2024 |
| Primary completion | 30 March 2026 |
| Estimated completion | 1 October 2026 |
Drugs / interventions tested
- Nasal elevator with digital nasoalveolar molding in bilateral cleft lip and palate infants
- Nasal stent with digital nasoalveolar molding in bilateral cleft lip and palate infants
Conditions studied
- Cleft Lip and Cleft Palate — all drugs for Cleft Lip and Cleft Palate →
Sponsor
Cairo University
Who can join
Adults 1 Day to 1 Month, any sex, with Cleft Lip and Cleft Palate. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Newborns with bilateral cleft lip/ palate will be treated pre-surgically by either nasal elevator or Grayson nasal stent in conjunction with digital nasoalveolar molding (D-NAM) appliance in order to evaluate their effect on the nasolabial esthetics.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06589453
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Cleft Lip and Cleft Palate
Currently open trials in the same condition.
- NCT07048418 — Aesthetic and Functional Self-Assessment Following Rhinoseptoplasty in Patients With Unilateral Cleft Lip and Palate · recruiting
Other Cairo University trials
Trials by the same sponsor.
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- NCT07363239 — CBCT-Based Safety Distance for Implant Placement Near the Inferior Alveolar Canal · not yet recruiting
- NCT07374575 — Egyptian Dental Professionals' Perspectives on the Oral Microbiome and Exosomes · not yet recruiting
- NCT07381153 — In-Vitro Cytotoxicity Assessment of INOX (Nanoksa G Plus) Polymer Discs · not yet recruiting
- NCT07375394 — 3D-Printed Extraoral Camera for Standardized Dental Photography · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06589453 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cairo University
- Last refreshed: 17 October 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06589453.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing