Last reviewed · How we verify
NCT06581588: THRIVE
Apneic Oxygenation by Transnasal Humidified Rapid Insufflation Ventilator Exchange Obstructive Sleep Apnea Patients
NA trial testing THRIVE in Obstructive Sleep Apnea Syndrome in 56 participants. Completed in 13 April 2025.
13 April 2025
Quick facts
| Lead sponsor | Beijing Tongren Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 56 |
| Start date | 1 September 2024 |
| Primary completion | 13 April 2025 |
| Estimated completion | 13 April 2025 |
| Sites | 1 location across China |
Drugs / interventions tested
- THRIVE
- THRIVE combine nasopharyngeal airway
Conditions studied
- Obstructive Sleep Apnea Syndrome — all drugs for Obstructive Sleep Apnea Syndrome →
Sponsor
Beijing Tongren Hospital
Who can join
Adults 18 to 75, any sex, with Obstructive Sleep Apnea Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of the study is to compare effectiveness of different methods of achieving oxygenation in obstructive sleep apnea patients. The investigators intend to compare transnasal humidified rapid-insufflation ventilator exchange (THRIVE) combined with nasopharyngeal airway with THRIVE alone.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Apneic oxygenation with Transnasal Humidified Rapid-insufflation Ventilator Exchange (THRIVE) in obstructive sleep apnea patients: study protocol of a randomized controlled trial.
Lei G, Wu L, Xi C, Yang S, et al · · 2025 · PMID 40217470 · DOI 10.1186/s12871-025-03055-5
Verify or expand the search:
- PubMed search for NCT06581588
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of THRIVE
Trials testing the same drug.
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- NCT05558891 — Pilot Study of a Brief, Recovery-focused Intervention for Crisis Stabilization Centers · NA · completed
Other recruiting trials for Obstructive Sleep Apnea Syndrome
Currently open trials in the same condition.
- NCT05147649 — Functional Magnetic Resonance Imaging in Patients With Obstructive Sleep Apnea Syndrome · NA · recruiting
Other Beijing Tongren Hospital trials
Trials by the same sponsor.
- NCT07499791 — Absorbable Drug-Eluting Lacrimal Sac Stent for Recurrent Chronic Dacryocystitis · Phase 2 · not yet recruiting
- NCT07524959 — Antagonism of Neostigmine in Continuous Infusion of Mivacurium · NA · not yet recruiting
- NCT07525466 — Combination of Mitoxantrone Liposome and Etoposide, Dexamethasone, Pegaspargase and Golidocitinib (MEPL-G) in the Treatm · Phase 1, PHASE2 · recruiting
- NCT07472764 — Auricular Acupressure for Reducing Postoperative Emergence Agitation in Preschool Children · NA · not yet recruiting
- NCT07523737 — Pomalidomide, Anti-PD-1 Antibody Combined With Selinexor (PPS) in Relapsed/Refractory Primary Central Nervous System Dif · Phase 2 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06581588 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Beijing Tongren Hospital
- Last refreshed: 17 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06581588.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing