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NCT06581367: STORM
Tailoring Antibiotic Duration for Respiratory Tract Infections in Primary Care
Phase 4 trial testing Tailoring the course duration to the patient's needs. in Acute Respiratory Tract Infection in 474 participants. Not yet recruiting.
30 March 2027
Quick facts
| Lead sponsor | Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina |
|---|---|
| Phase | Phase 4 |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 474 |
| Start date | 1 October 2025 |
| Primary completion | 30 March 2027 |
| Estimated completion | 30 April 2027 |
Drugs / interventions tested
- Tailoring the course duration to the patient's needs. — full drug profile →
- Complete a 7-day course — full drug profile →
Conditions studied
- Acute Respiratory Tract Infection — all drugs for Acute Respiratory Tract Infection →
Sponsor
Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina — full company profile →
Who can join
Adults 18 to 75, any sex, with Acute Respiratory Tract Infection. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The rise of drug-resistant organisms and the need to minimize side effects calls for a new approach to antibiotic therapy duration. This study explores tailoring the length of antibiotic treatment to patient recovery, focusing on whether adjusting therapy based on when the patient feels better is as effective as completing the prescribed course for acute respiratory tract infections (RTIs). The investigators will enroll 474 outpatients aged 18-75 with acute RTIs across 25 Spanish healthcare centers. Patients will be randomized into two groups: one following standard full-course antibiotic therapy, and another receiving a tailored approach, where treatment may be shortened based on clinical assessments. The primary outcome is clinical efficacy at day 14. Secondary outcomes include antibiotic duration, complications, and quality of life.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Tailoring Antibiotic Duration for Respiratory Tract Infections in Primary Care: Protocol for a Pragmatic Randomized Controlled Trial Study (STORM).
Morros R, Moragas A, García-Sangenís A, Monfà R, et al · · 2025 · PMID 41115271 · DOI 10.2196/75453
Verify or expand the search:
- PubMed search for NCT06581367
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Acute Respiratory Tract Infection
Currently open trials in the same condition.
- NCT05814237 — POS-ARI-ER Observational Study of Acute Respiratory Infections · recruiting
Other Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06581367 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
- Last refreshed: 3 September 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06581367.
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