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NCT06579768

Radiomics for Preoperative Jaw Cyst Differentiation

Recruiting now Last updated 19 September 2024
What this trial tests

trial testing different types of computed tomography (CT) scans in Jawbone Cysitc Lesion in 300 participants. Currently enrolling.

Timeline
5 September 2024
Primary endpoint
30 June 2025
1 January 2026

Quick facts

Lead sponsorSun Yat-Sen Memorial Hospital of Sun Yat-Sen University
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment300
Start date5 September 2024
Primary completion30 June 2025
Estimated completion1 January 2026
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Who can join

Eligibility, any sex, with Jawbone Cysitc Lesion. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study focuses on jawbone cystic lesions, including odontogenic tumors like ameloblastoma and various cysts. Treatment approaches differ; ameloblastomas often require surgical excision due to potential recurrence and metastasis, while cystic lesions may be treated with curettage and marsupialization. Accurate preoperative diagnosis is crucial for optimal treatment outcomes, as inappropriate choices can lead to delayed treatment or overtreatment, affecting patient quality of life. Currently, there is no standard protocol for differential diagnosis, highlighting the need for a predictive diagnostic model. The study will be a multicenter, prospective machine learning research involving 300 patients across 12 centers. It aims to enhance a previously developed predictive model that integrates machine learning with CT radiomics. Patients will be grouped based on imaging modalities, with data processed uniformly to improve diagnostic predictions. Inclusion criteria ensure comprehensive preoperative data, while exclusion criteria eliminate incomplete or previously treated cases. The study seeks to optimize the model's performance and provide valuable clinical insights.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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