Last reviewed · How we verify
NCT06576427: SPIRARE II
Selective Pulmonary-artery Intervention to Reduce Acute Right-heart tEnsion-II
NA trial testing Vertex Pulmonary Embolectomy System in Pulmonary Embolism in 123 participants. Completed in 3 March 2026.
4 February 2026
Quick facts
| Lead sponsor | Jupiter Endovascular |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 123 |
| Start date | 15 October 2024 |
| Primary completion | 4 February 2026 |
| Estimated completion | 3 March 2026 |
| Sites | 23 locations across Switzerland, Austria, United States, Poland |
Drugs / interventions tested
- Vertex Pulmonary Embolectomy System
Conditions studied
- Pulmonary Embolism — all drugs for Pulmonary Embolism →
Sponsor
Jupiter Endovascular
Who can join
Adults 18 to 79, any sex, with Pulmonary Embolism. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is a prospective, single-arm, multicenter study to evaluate the safety and effectiveness of the Vertex Pulmonary Embolectomy System in participants presenting with clinical signs and symptoms of acute pulmonary embolism.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06576427
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Vertex Pulmonary Embolectomy System
Trials testing the same drug.
- NCT06571760 — Selective Pulmonary-artery Intervention to Reduce Acute Right-heart tEnsion-I · NA · completed
Other recruiting trials for Pulmonary Embolism
Currently open trials in the same condition.
- NCT07381712 — High-Flow Nasal Cannula Versus Non-Invasive Ventilation for Acute Respiratory Failure in Pulmonary Embolism. · NA · active not recruiting
- NCT04211181 — CHIPs-VTE Study in Hospitalized Patients to Prevent Hospital-Acquired Venous Thromboembolism · NA · recruiting
- NCT07003646 — Reperfusion Treatment in Acute Pulmonary Embolism · recruiting
- NCT06600542 — Inari VISION Registry · recruiting
- NCT06622876 — Incidental Discovery of Pulmonary Emboli Via CT Scan: Impact of Detections on Patient Care and Resulting Complications · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06576427 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Jupiter Endovascular
- Last refreshed: 6 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06576427.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing