NCT06575712 is a NA clinical trial of Step Up in Hematopoietic Stem Cell Transplant, sponsored by Duke University.

Who is sponsoring NCT06575712?

NCT06575712 is sponsored by Duke University.

What drugs are being tested in NCT06575712?

Interventions in NCT06575712: Step Up, Usual Care Plus (UC+).

What condition does NCT06575712 study?

NCT06575712 studies Hematopoietic Stem Cell Transplant, CAR-T Cell Therapy.

Is NCT06575712 still recruiting?

NCT06575712 is currently recruiting now. Last updated 9 April 2026.

Last reviewed 2026-04-09 · How we verify

NCT06575712

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Coping Skills Training for Symptom Management and Daily Steps (Step Up)

Recruiting now NA Last updated 9 April 2026

What this trial tests

NA trial testing Step Up in Hematopoietic Stem Cell Transplant in 177 participants. Currently enrolling.

Timeline

21 April 2025

Primary endpoint
31 August 2028

31 August 2028

Quick facts

Lead sponsor	Duke University
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	supportive care
Enrollment	177
Start date	21 April 2025
Primary completion	31 August 2028
Estimated completion	31 August 2028
Sites	1 location across United States

Drugs / interventions tested

Step Up
Usual Care Plus (UC+)

Conditions studied

Hematopoietic Stem Cell Transplant — all drugs for Hematopoietic Stem Cell Transplant →
CAR-T Cell Therapy — all drugs for CAR-T Cell Therapy →

Sponsor

Duke University

Who can join

Adults 18 to 99, any sex, with Hematopoietic Stem Cell Transplant or CAR-T Cell Therapy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to test the efficacy of a hybrid in-person and mHealth coping skills training and activity coaching intervention (Step Up), to enable HCT patients to effectively cope with symptoms (pain, fatigue, and stress) to improve their ability to engage in physical activity that can improve physical disability.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Hybrid-delivered cognitive behavioral symptom management and activity coaching intervention for patients following hematopoietic stem cell transplant or CAR T-cell therapy: Protocol of a randomized controlled trial.
Pedreira PB, Somers TJ, Fisher HM, Winger JG, et al · · 2026 · PMID 42070654 · DOI 10.1016/j.cct.2026.108332

Verify or expand the search:

Other recruiting trials for Hematopoietic Stem Cell Transplant

Currently open trials in the same condition.

NCT06328127 — Positive Psychology Intervention for Hematopoietic Stem Cell Transplantation Survivors · NA · recruiting
NCT06462365 — Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT) · Phase 1 · recruiting
NCT03613532 — Venetoclax Added to Fludarabine + Busulfan Prior to Transplant and to Maintenance Therapy for AML, MDS, and MDS/MPN · Phase 1 · active not recruiting

Other Duke University trials

Trials by the same sponsor.

NCT07216456 — Vaginal Dilator Therapy After Pelvic Radiation · NA · not yet recruiting
NCT07519317 — Dosing and Deployment Trial: A Home-based Optokinetic Treatment · NA · not yet recruiting
NCT07275359 — Investigating Senolytic Properties in Pulmonary Rehabilitation and Metformin in COPD Exacerbations · Phase 1 · not yet recruiting
NCT07216963 — The Community Paramedic Response and Overdose Outreach With Supportive Medical-Legal Services Study · NA · not yet recruiting
NCT07459218 — IDEAS for Hope to Reduce Suicide Risk and Improve HIV Care Engagement in Tanzania · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06575712 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Duke University
Last refreshed: 9 April 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06575712.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing