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NCT06572072
Effects of Negative Pressure Ventilation on Right Ventricular Function in Cardiological Patients
trial testing Negative Pressure Ventilation in Negative Pressure Ventilation in 30 participants. Not yet recruiting.
1 September 2025
Quick facts
| Lead sponsor | Karlsburg Hospital |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 30 |
| Start date | 1 September 2024 |
| Primary completion | 1 September 2025 |
| Estimated completion | 1 September 2025 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- Negative Pressure Ventilation
Conditions studied
- Negative Pressure Ventilation — all drugs for Negative Pressure Ventilation →
- Right Ventricular Dysfunction — all drugs for Right Ventricular Dysfunction →
- Right Ventricular Failure — all drugs for Right Ventricular Failure →
Sponsor
Karlsburg Hospital
Who can join
18 and older, any sex, with Negative Pressure Ventilation or Right Ventricular Dysfunction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Patients receives induction of general anesthesia for interventional tricuspidal clipping and standard monitoring for this procedure including arterial and central venous line and transesophageal ultrasound. A cuirass for extrathoracal negative pressure ventilation is placed onto the chest but not switched on. During usual positive pressure ventilation a ventilatory, a hemodynamic and a 3D full volume ultrasounddataset of the right and left ventricle is recorded and severity of tricuspidal regurgitation examined. Afterwards negative pressure ventilation is started and positive pressure ventilation reduced as far as possible without reduction of tidal volumes. The same dataset of ventilation, hemodynamics and ultrasound is collected again during negative pressure ventilation. Afterwards the cuirass gets removed, study finished and everything proceeds as during standard procedure.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06572072
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Karlsburg Hospital trials
Trials by the same sponsor.
- NCT07034599 — Effects of Negative Pressure Ventilation Onto Hemodynamics and Right Ventricular Funktion in Patients After Implantation · NA · recruiting
- NCT06918301 — Comparison of Cardiac Index and Stroke-volume-index Measured by Pulmonary Artery Catheter, FloTrac® and Argos® in Cardia · recruiting
- NCT06088966 — Evaluation of Hemodynamic and Ventilatory Effects of Negative Pressure Ventilation · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06572072 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Karlsburg Hospital
- Last refreshed: 26 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06572072.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing