Last reviewed · How we verify
VItamin D in pregnanCy for prevenTion Of eaRlY Childhood Asthma (VICTORY)
The overall aim of the study is to develop a nutritional preventive vitamin D supplementation strategy in pregnancy for early childhood asthma/persistent wheeze during the first three years of life as we hypothesize that supplementation in higher doses than recommended could reduce the risk of disease development.
Details
| Lead sponsor | Professor Klaus Bønnelykke |
|---|---|
| Phase | Phase 3 |
| Status | RECRUITING |
| Enrolment | 2000 |
| Start date | 2024-12-20 |
| Completion | 2033-03 |
Conditions
- Asthma
- Respiratory Tract Infections
- Gastrointestinal Infection
- Croup
- Eczema
- Allergy
- Wheezing
- Fractures, Bone
- Development, Child
- Cognition Disorders in Children
Interventions
- Cholecalciferol D3
- Olive oil
Primary outcomes
- Early childhood asthma/persistent wheeze age 0-3 years — 3 years
Defined as either a) parental report of a minimum of 2 wheeze episodes with at least 1 after the child's second birthday and redemption of at least 2 prescriptions of asthma controller medication with at least 1 being after the child's second birthday or b) a minimum of 2 ED visits or hospitalizations due to asthmatic symptoms, and at least 1 of these being after the child's second birthday or c) parental report of physician-diagnosed asthma age 0-3 years Outcome analysis: risk (survival analysis) of persistent wheeze or asthma at age 0-3 years.
Countries
Denmark