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NCT06569095

Predictive Value of Myelodysplastic Syndrome Stem Cells Determined by Multiparameter Flow Cytometry

Recruiting now Last updated 24 February 2026
What this trial tests

trial testing Detection of MDS-SC using MFC in Myelodysplastic Syndromes in 163 participants. Currently enrolling.

Timeline
9 December 2024
Primary endpoint
17 December 2027
18 December 2027

Quick facts

Lead sponsorPeking University People's Hospital
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment163
Start date9 December 2024
Primary completion17 December 2027
Estimated completion18 December 2027
Sites4 locations across China

Drugs / interventions tested

Conditions studied

Sponsor

Peking University People's Hospital

Who can join

Adults 15 to 70, any sex, with Myelodysplastic Syndromes. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Presently, multiparameter flow cytometry (MFC) and polymerase chain reaction (PCR) have been used for disease load, including measurable residual disease (MRD), monitoring in patients with myelodysplastic syndrome (MDS). MFC is the most commonly method for disease load evaluation. In patients with acute myeloid leukemia, leukemia stem cells (LSCs) determined using MFC for leukemia load and MRD detection is superior to traditional MFC method. In the investigators previous single center study, the investigators demonstrated that detection of disease load, including MRD, by MFC in patients with MDS-EB is superior to predict outcomes after allogeneic stem cell transplantation. Here, the investigators will perform a multi-center, prospective clinical trial to investigate the predictive values of MDS-SC in patients with MDS-EB who received allografting.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Myelodysplastic Syndromes

Currently open trials in the same condition.

Other Peking University People's Hospital trials

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Data sources for this page

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