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NCT06568731
A Study to Learn How Different Amounts of the Study Medicine Danuglipron Are Taken up Into the Blood in Otherwise Healthy Adults With Overweight or Obesity
Phase 1 trial testing Danuglipron in Obesity in 23 participants. Completed in 18 December 2024.
18 December 2024
Quick facts
| Lead sponsor | Pfizer |
|---|---|
| Phase | Phase 1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 23 |
| Start date | 23 August 2024 |
| Primary completion | 18 December 2024 |
| Estimated completion | 18 December 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Danuglipron (danuglipron) — full drug profile →
Conditions studied
- Obesity — all drugs for Obesity →
Sponsor
Pfizer — full company profile →
Who can join
18 and older, any sex, with Obesity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to learn the following about the study medicine, danuglipron, after multiple days of dosing in healthy adults who are overweight or obese: * how the study medicine, danuglipron, is taken up into the blood * about the safety and tolerability of danuglipron The total number of weeks of the study is about 15 (about 4 months).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Oral Treatment of Obesity by GLP-1 and Its Analogs.
Holler N, Ruseska I, Schachner-Nedherer AL, Zimmer A, et al · · 2025 · PMID 41471111 · DOI 10.3390/pharmaceutics17121596
Verify or expand the search:
- PubMed search for NCT06568731
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Danuglipron
Trials testing the same drug.
- NCT06541678 — A Study to Learn if the Study Medicines Called Itraconazole and Cyclosporine Change How the Body Processes the Other Stu · Phase 1 · completed
- NCT06567327 — A Study to Learn How the Study Medicine Danuglipron is Taken Up Into the Blood and If Danuglipron Changes How the Body P · Phase 1 · completed
- NCT06153758 — Study to Learn How Different Forms of The Study Medicine Called Danuglipron Are Taken up Into the Blood In Healthy Adult · Phase 1 · completed
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Currently open trials in the same condition.
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Other Pfizer trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06568731 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Pfizer
- Last refreshed: 20 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06568731.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing