Last reviewed · How we verify
NCT06567522
Comparative Assessment of Effectiveness and Safety of L-ESPB Versus Absence of Locoregional Block in Hip Surgery
Phase 4 trial testing Lumbar Erector Spinae Plane Block. L bupivacaína 0.25% in Hip Fractures in 180 participants. Currently enrolling.
31 December 2025
Quick facts
| Lead sponsor | Hospital Álvaro Cunqueiro |
|---|---|
| Phase | Phase 4 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | supportive care |
| Enrollment | 180 |
| Start date | 8 June 2024 |
| Primary completion | 31 December 2025 |
| Estimated completion | 31 December 2025 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Lumbar Erector Spinae Plane Block. L bupivacaína 0.25% — full drug profile →
Conditions studied
- Hip Fractures — all drugs for Hip Fractures →
- Lumbar Erector Spinae Plane Block — all drugs for Lumbar Erector Spinae Plane Block →
Sponsor
Hospital Álvaro Cunqueiro
Who can join
18 and older, any sex, with Hip Fractures or Lumbar Erector Spinae Plane Block. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Hip surgery accounts for a high percentage of both emergency and elective surgical procedures in hospitals. Regardless of surgery being prescribed to treat a fracture or coxarthrosis, patients are usually elderly with multiple associated comorbidities. When faced with this patient profile, there is a tendency to undertreat pain for fear of the side effects and pharmacological interactions of conventional analgesic drugs. Ultrasound-guided regional anesthesia applied in orthopedic and trauma surgery has been shown to reduce the doses of opioids and conventional analgesics, to ease deambulation and early recovery, to improve respiratory dynamics and to reduce vein thrombosis and pneumonias. Our study aims to verify whether L-ESP block is effective in the hip and proximal femur surgeries and allows to lower the dosage of opioids in these patients.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effectiveness and Safety of Lumbar Erector Spinae Plane Block Versus No Locoregional Block in Hip Surgery: Protocol for a Randomized Controlled Trial.
García-Reza L, Raposeiras S, P Loureiro J, Pita-Romero R, et al · · 2025 · PMID 40953436 · DOI 10.2196/75854
Verify or expand the search:
- PubMed search for NCT06567522
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Hip Fractures
Currently open trials in the same condition.
- NCT07239817 — PENG Block + LIA For Endoprosthesis Surgery With Anterior Approach · NA · recruiting
- NCT07002723 — Effects of Esketamine Combined With Dexmedetomidine on Postoperative Sleep Quality · NA · recruiting
- NCT06893406 — Cervical Myelopathy in Hip Fracture Patients · NA · recruiting
- NCT06565910 — Bupivacaine Liposome Plus Bupivacaine or Ropivacaine for Pericapsular Nerve Group Block in Hip Arthroplasty (PENG) · Phase 4 · recruiting
- NCT06455813 — What Laxative Should be Used After Hip Fracture Surgery? · Phase 4 · recruiting
Other Hospital Álvaro Cunqueiro trials
Trials by the same sponsor.
- NCT04364516 — Retrospective Observational Registry of Patients With Atrial Fibrillation From Vigo´s Health Area · unknown
- NCT03664388 — Registry of Acute Coronary Syndrome From University Hospital of Vigo · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06567522 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hospital Álvaro Cunqueiro
- Last refreshed: 22 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06567522.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing