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NCT06567145: NECT-ITA
A Group-based Treatment for Self-stigma in People With Mental Disorders in North-east Italy
NA trial testing Narrative Enhancement Cognitive Therapy (NECT) in Stigma in 416 participants. Currently enrolling.
1 October 2025
Quick facts
| Lead sponsor | Universita di Verona |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 416 |
| Start date | 1 October 2024 |
| Primary completion | 1 October 2025 |
| Estimated completion | 1 October 2025 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Narrative Enhancement Cognitive Therapy (NECT)
Conditions studied
- Stigma — all drugs for Stigma →
- Mental Disorders — all drugs for Mental Disorders →
- Self-stigma — all drugs for Self-stigma →
Sponsor
Universita di Verona — full company profile →
Who can join
18 and older, any sex, with Stigma or Mental Disorders. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Self-stigma refers to the internalization of negative stereotypes by individuals with mental disorders, leading to beliefs that they are dangerous, aggressive, or incapable of working. This phenomenon has harmful effects on various aspects of life, such as adherence to treatment, self-esteem, quality of life, and can increase feelings of despair and suicide risk. To address these issues, the Narrative Enhancement and Cognitive Therapy (NECT) was developed. NECT is a group-based intervention consisting of 20 sessions designed to reduce self-stigma in individuals with mental disorders. This study aims to evaluate the efficacy and feasibility of NECT in 416 patients from 26 mental health centers in Northeast Italy. It is structured as a pragmatic, multicenter, randomized controlled trial with two parallel arms. The study will assess the impact of NECT on several psychological dimensions, including levels of self-stigma, self-esteem, hope, empowerment, perception of recovery, mental well-being, and stigma-related stress. The findings of this research are expected to contribute to the understanding of effective treatments for patients with mental disorders, particularly those burdened by high levels of self-stigma, and to improve their recovery outcomes.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Assessing the effectiveness and the feasibility of a group-based treatment for self-stigma in people with mental disorders in routine mental health services in North-East Italy: study protocol for a pragmatic multisite randomized controlled trial.
Lasalvia A, Bodini L, Cristofalo D, Fin V, et al · · 2025 · cited 1× · PMID 39891254 · DOI 10.1186/s13063-025-08739-4
Verify or expand the search:
- PubMed search for NCT06567145
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06567145 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universita di Verona
- Last refreshed: 26 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06567145.
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