NCT06566677 (PROVE) is a clinical trial in Chlamydia Trachomatis Genital Infection, sponsored by Wits RHI Research Centre Clinical Research Site.

Who is sponsoring NCT06566677?

NCT06566677 is sponsored by Wits RHI Research Centre Clinical Research Site.

What condition does NCT06566677 study?

NCT06566677 studies Chlamydia Trachomatis Genital Infection, Gonorrhea, Trichomoniasis.

Is NCT06566677 still recruiting?

NCT06566677 is currently completed. Last updated 26 August 2024.

Last reviewed 2024-08-26 · How we verify

NCT06566677: PROVE

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Point of Care Rapid STI Test Optimization and Validation Extension

Completed Last updated 26 August 2024

What this trial tests

trial in Chlamydia Trachomatis Genital Infection in 364 participants. Completed in 7 December 2023.

Timeline

26 January 2023

Primary endpoint
7 December 2023

7 December 2023

Quick facts

Lead sponsor	Wits RHI Research Centre Clinical Research Site
Status	Completed
Study type	OBSERVATIONAL
Enrollment	364
Start date	26 January 2023
Primary completion	7 December 2023
Estimated completion	7 December 2023
Sites	1 location across South Africa

Conditions studied

Chlamydia Trachomatis Genital Infection — all drugs for Chlamydia Trachomatis Genital Infection →
Gonorrhea — all drugs for Gonorrhea →
Trichomoniasis — all drugs for Trichomoniasis →

Sponsor

Wits RHI Research Centre Clinical Research Site

Who can join

Adults 18 to 25, female only, with Chlamydia Trachomatis Genital Infection or Gonorrhea. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this sub-study (PROVE) is to support and facilitate the validation of commercially available point of care (POC) sexually transmitted infection (STI) diagnostic test kits/devices for potential on-site laboratory use as well as bedside use in parallel to gold standard established testing methodologies. A further extension of bedside testing would include self-testing.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Validation of Rapid Point-of-Care Diagnostic Tests for Sexually Transmitted Infection Self-Testing Among Adolescent Girls and Young Women.
Reddy K, Hao J, Sigcu N, Govindasami M, et al · · 2025 · cited 1× · PMID 40647603 · DOI 10.3390/diagnostics15131604

Verify or expand the search:

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06566677 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Wits RHI Research Centre Clinical Research Site
Last refreshed: 26 August 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06566677.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing