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NCT06565143
Effect of Transcranial Alternating Current Stimulation(tACS) for Early Alzheimer's Disease
NA trial testing Transcranial alternating current stimulation in Transcranial Alternating Current Stimulation in 40 participants. Currently enrolling.
1 March 2026
Quick facts
| Lead sponsor | Anhui Medical University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | basic science |
| Enrollment | 40 |
| Start date | 1 March 2024 |
| Primary completion | 1 March 2026 |
| Estimated completion | 1 July 2026 |
| Sites | 1 location across China |
Drugs / interventions tested
- Transcranial alternating current stimulation
- Sham transcranial alternating current stimulation
Conditions studied
- Transcranial Alternating Current Stimulation — all drugs for Transcranial Alternating Current Stimulation →
- Electroencephalography — all drugs for Electroencephalography →
- Early Alzheimer's Disease — all drugs for Early Alzheimer's Disease →
Sponsor
Anhui Medical University
Who can join
Adults 50 to 85, any sex, with Transcranial Alternating Current Stimulation or Electroencephalography. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To investigate the clinical effect neural mechanism of transcranial alternating current stimulation in early Alzheimer's disease
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Individualized frequency and montage tACS to engage theta-gamma coupling and enhance working memory in mild cognitive impairment.
Mirjalili M, Palamarchuk IS, Brooks H, Zomorrodi R, et al · · 2025 · cited 2× · PMID 40530065 · DOI 10.3389/fpsyt.2025.1565881 -
Effects of 40-Hz transcranial alternating current stimulation on cognition and neural markers in Alzheimer's disease: a randomized, sham-controlled trial.
Fang M, Yan Y, Song W, Geng Z, et al · · 2026 · PMID 41918026 · DOI 10.1186/s13195-026-02033-4
Verify or expand the search:
- PubMed search for NCT06565143
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Transcranial alternating current stimulation
Trials testing the same drug.
- NCT06740864 — 40 Hz Transcranial Alternating Current Stimulation for Inducing Gamma Oscillations · NA · completed
- NCT04856657 — Targeting Individual Alpha Frequencies to Enhance Perceptual Timing · completed
- NCT06680154 — Induction and Stabilization of Gamma Oscillations With 40 Hz External Brain Stimulation · NA · completed
- NCT04646499 — Feasibility of Gamma Transcranial Alternating Current Stimulation to Reduce Beta-amyloid Load and Improve Memory · NA · completed
- NCT04647032 — Enhancing Cognitive Control in Mild Cognitive Impairment Via Non-invasive Brain Stimulation · NA · completed
Other recruiting trials for Transcranial Alternating Current Stimulation
Currently open trials in the same condition.
- NCT07087873 — Assessment of Transcranial Alternating Current Stimulation's Clinical Efficacy in Treating Cognitive Impairment of Idiop · NA · recruiting
- NCT06874374 — Individualized Non-invasive Brain Stimulation for the Treatment of Major Depressive Disorder · NA · active not recruiting
- NCT06888726 — Efficacy of Hi-tACS for Schizophrenia Negative Symptoms · NA · recruiting
Other Anhui Medical University trials
Trials by the same sponsor.
- NCT07403591 — Mapsd Dual-target cTBS (Auditory Cortex and M1) for Generalized Anxiety Disorder · NA · not yet recruiting
- NCT07112612 — Minimal Residual Disease Used in Predicting Therapeutic Efficacy in Metastatic Hormone-sensitive Prostate Cancer · not yet recruiting
- NCT07112599 — Study of Predicting Lymph Node Metastasis of High-risk Prostate Cancer by Artificial Intelligence Multi-omics Analysis · recruiting
- NCT07176468 — Personalized iTBS in Real-World Clinical Settings for Schizophrenia · NA · recruiting
- NCT07486804 — Effects of taVNS Combined With tACS on Adolescents With Non-Suicidal Self-Injury · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06565143 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Anhui Medical University
- Last refreshed: 21 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06565143.
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