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NCT06564402: APEX
Augmentation of Exposure Using Positive Mental Rehearsal in Individuals With Increased Social Anxiety
NA trial testing Positive Mental Rehearsal in Social Anxiety in 40 participants. Currently enrolling.
1 February 2026
Quick facts
| Lead sponsor | Philipps University Marburg |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 28 May 2024 |
| Primary completion | 1 February 2026 |
| Estimated completion | 1 March 2026 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- Positive Mental Rehearsal
- Mental Rehearsal
- Exposure
Conditions studied
- Social Anxiety — all drugs for Social Anxiety →
- Social Phobia — all drugs for Social Phobia →
Sponsor
Philipps University Marburg
Who can join
18 and older, any sex, with Social Anxiety or Social Phobia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Efficacy of an optimized exposure therapy training is investigated in individuals with heightened social anxiety. Participants will undergo a one-session standardized exposure training, followed by either standard or positive mental rehearsal of the exposure experience. The efficacy is measured by symptom improvement according to subjective ratings one week later.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06564402
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Social Anxiety
Currently open trials in the same condition.
- NCT06934525 — Implementing Team-Based Treatment for Pediatric Anxiety in Community Mental Health Settings · NA · recruiting
- NCT07259005 — Breathe Hard to Breathe Easy: Online Breathwork-Assisted Therapy for Social Anxiety · NA · recruiting
- NCT06465589 — Variations of Anonymity, Transparency, and Efficacy in Digital Health Applications · NA · active not recruiting
- NCT06409247 — iExposure Intervention for Social Anxiety · NA · active not recruiting
- NCT05704868 — UniVRse: VR-CBT for Students With Social Anxiety · NA · recruiting
Other Philipps University Marburg trials
Trials by the same sponsor.
- NCT07498803 — Sota-ES - Sotatercept in Patients With Congenital Heart Disease and Eisenmenger´s Syndrome · Phase 2 · not yet recruiting
- NCT07388004 — Group Therapy for Major Depression: Comparing Expectation-Focused and Reward-Focused Psychotherapy Approaches · NA · recruiting
- NCT07166692 — Evaluation of a Retrieval Augmented Large Language Model as a Diagnostic Copilot in Rheumatology · NA · completed
- NCT06865534 — Large Language Models to Aid Gynecological Oncology Treatment · NA · recruiting
- NCT06968897 — Neurological Development In Toddlers After Maternal SARS-CoV-2 Infection During Pregnancy · enrolling by invitation
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06564402 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Philipps University Marburg
- Last refreshed: 9 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06564402.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing