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NCT06564259

Relationship Between Serum β2-Microglobulin and Infiltration of CD8+ in the Tumor Tissue of Hodgkin's Lymphoma Patients

Completed Last updated 21 August 2024
What this trial tests

trial in Hodgkin Lymphoma in 144 participants. Completed in 15 August 2024.

Timeline
4 January 2024
Primary endpoint
15 August 2024
15 August 2024

Quick facts

Lead sponsorTishreen University
StatusCompleted
Study typeOBSERVATIONAL
Enrollment144
Start date4 January 2024
Primary completion15 August 2024
Estimated completion15 August 2024
Sites1 location across Syria

Conditions studied

Sponsor

Tishreen University

Who can join

Eligibility, any sex, with Hodgkin Lymphoma. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In newly diagnosed Hodgkin lymphoma patients, pre-treatment Beta-2 Microglobulin (B2M) levels will be measured. A thorough baseline assessment will be performed using CT imaging, and tumor tissue samples will be collected for Immunohistochemical (IHC) analysis to quantify CD8+ cell infiltration. Patients will be closely monitored throughout their treatment, with a follow-up CT scan at the end of therapy to evaluate therapeutic response. This study aims to investigate the correlation between pre-treatment B2M levels and CD8+ immune cell infiltration in tumor tissues, assessing their potential as predictive markers for chemotherapy response.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other recruiting trials for Hodgkin Lymphoma

Currently open trials in the same condition.

Other Tishreen University trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06564259.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing