Last reviewed · How we verify
NCT06562725: VentSetFib
Ventilator Settings for Bronchoscopy During Mechanical Ventilation: a Randomized Controlled Study
NA trial testing specific ventilator settings in Mechanical Ventilation Complication in 46 participants. Completed in 19 June 2025.
12 June 2025
Quick facts
| Lead sponsor | Centre Hospitalier Arras |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 46 |
| Start date | 10 September 2024 |
| Primary completion | 12 June 2025 |
| Estimated completion | 19 June 2025 |
| Sites | 1 location across France |
Drugs / interventions tested
- specific ventilator settings
Conditions studied
- Mechanical Ventilation Complication — all drugs for Mechanical Ventilation Complication →
- Fiberoptic Bronchoscopy — all drugs for Fiberoptic Bronchoscopy →
- Critical Illness — all drugs for Critical Illness →
- Acute Respiratory Failure — all drugs for Acute Respiratory Failure →
Sponsor
Centre Hospitalier Arras
Who can join
18 and older, any sex, with Mechanical Ventilation Complication or Fiberoptic Bronchoscopy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Fiberoptic bronchoscopy (FOB) can cause a significant increase in respiratory resistances and airway pressure during mechanical ventilation (MV), which can jeopardize the delivery of the ventilatory assistance. This randomized controlled study tests the hypothesis that new ventilator settings aimed at reducing airway pressure may facilitate FOB during MV. Results of this trial should lead to propose a new ventilatory strategy for critically ill patients needing a FOB procedure under MV.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Ventilator settings for fibreoptic bronchoscopy during mechanical ventilation: a study protocol for a pragmatic randomised double-blind controlled trial VentSetFib.
Lemyze M, Granier M, Laouki CE, Belmeguenai A, et al · · 2025 · cited 1× · PMID 40010841 · DOI 10.1136/bmjopen-2024-096164
Verify or expand the search:
- PubMed search for NCT06562725
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Mechanical Ventilation Complication
Currently open trials in the same condition.
- NCT06921655 — Targeting prEssure-Muscle-index to Avoid Ventilatory Over-Assistance During Pressure Support Ventilation · NA · recruiting
- NCT07207772 — EIT-guided PEEP Titration Versus Standard Ventilation in Bariatric Surgery · NA · recruiting
- NCT07182851 — Prevalence of Pain in Mechanically Ventilated Patients in Intensive Care Units · recruiting
- NCT06575530 — Sedation Efficacy and Safety of Remazolam Besylate in Ventilated Surgical Critically Ill Patients · Phase 4 · recruiting
- NCT06592144 — TESTO-TRIAL: Use of Testosterone in Critically Ill Patients · Phase 4 · active not recruiting
Other Centre Hospitalier Arras trials
Trials by the same sponsor.
- NCT05358067 — Predictability of the Clinical Global Impression Scale (CGI) in Post Immediate in Psychotraumatic Impact · recruiting
- NCT04588610 — Severe Obesity and Eating Habits (OSCAR) · completed
- NCT04391686 — Resting Energy Expenditure of the COronaVirus (COVID19) Patient in Reanimation Context · completed
- NCT04102735 — Under the Nose Face Mask to Prevent Facial Pressure Ulcers During NIV for Acute Hypercapnic Respiratory Failure (AHRF) · NA · completed
- NCT03610074 — Relieve the Patient's Thirst, Refresh the Mouth First (ICU-MIC) · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06562725 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Arras
- Last refreshed: 8 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06562725.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing