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NCT06551688

Influence of Preoperative Vitamin D Level on Postoperative Pain in Breast Cancer Surgery Patients

Completed Last updated 6 May 2025
What this trial tests

trial testing Serum 25(OH)D level in Cancer Breast in 184 participants. Completed in 20 April 2025.

Timeline
1 September 2024
Primary endpoint
20 April 2025
20 April 2025

Quick facts

Lead sponsorFayoum University
StatusCompleted
Study typeOBSERVATIONAL
Enrollment184
Start date1 September 2024
Primary completion20 April 2025
Estimated completion20 April 2025
Sites1 location across Egypt

Drugs / interventions tested

Conditions studied

Sponsor

Fayoum University

Who can join

Adults 20 to 65, female only, with Cancer Breast or Hypovitaminosis D. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Vitamin D deficiency is a general problem that vigorously affects human health . Breast cancer is the most frequently diagnosed life-threatening cancer in women and the leading cause of cancer death among women.Vitamin D deficiency is common in breast cancer patients and some evidence suggests that low vitamin D status enhances the risk for disease development or progression . Though the relationship between vitamin D and breast cancer is unclear . Several research studies currently support vitamin D deficiency as a risk factor for breast cancer. Observational studies have also revealed significant relationships of vitamin D with breast cancer, colorectal cancer, prostate cancer and pancreatic cancer . However, no work has been done to investigate the relationship between vitamin D deficiency and acute postoperative pain in breast cancer surgery patients. In the current study we will investigate the relationship between preoperative vitamin D levels and acute postoperative pain in cancer breast surgery patients. The aim of current study is to investigate the relationship between preoperative vitamin D levels and acute postoperative pain in breast cancer surgery patients.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. The Effects of Vitamin D on the Breast Cancer Tumor Microenvironment.
    Kanwal B, Shah SS, Shaheen F, Shiferaw MS, et al · · 2025 · PMID 41374952 · DOI 10.3390/cancers17233751
  2. Vitamin D, immune microenvironment, and cervical lesions: mechanisms and therapeutic strategies from polyps to carcinoma.
    He Z, Du C. · · 2025 · PMID 41245397 · DOI 10.3389/fnut.2025.1688910

Verify or expand the search:

Other recruiting trials for Cancer Breast

Currently open trials in the same condition.

Other Fayoum University trials

Trials by the same sponsor.

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Data sources for this page

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