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NCT06551415
Dabigatran Versus Apixaban in Cerebral Venous Thrombosis
Phase 3 trial testing Dabigatran Etexilate 150mg in Cerebral Venous Sinus Thrombosis in 200 participants. Currently enrolling.
1 September 2024
Quick facts
| Lead sponsor | Kafrelsheikh University |
|---|---|
| Phase | Phase 3 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 200 |
| Start date | 1 August 2021 |
| Primary completion | 1 September 2024 |
| Estimated completion | 1 October 2024 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Dabigatran Etexilate 150mg — full drug profile →
- Apixaban 5MG — full drug profile →
Conditions studied
- Cerebral Venous Sinus Thrombosis — all drugs for Cerebral Venous Sinus Thrombosis →
Sponsor
Kafrelsheikh University
Who can join
Adults 18 to 75, any sex, with Cerebral Venous Sinus Thrombosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Along with the current clinical trial, the efficacy and safety of a 150 mg Bid dabigatran administered within 24 hours of randomization after having first-ever cerebral venous thrombosis compared to apixaban 5mg Bid were assessed through rate of recurrent VTE, mRS, rate of venous recanalization, HIT score, MoCA test, and central and peripheral hemorrhagic complications
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Direct Oral Anticoagulants for the Treatment of Unusual-Site Venous Thrombosis: An Update.
Franco-Moreno A, Madroñal-Cerezo E, Martínez-Casa-Muñoz A, Ortiz-Sánchez J, et al · · 2025 · cited 1× · PMID 40143006 · DOI 10.3390/pharmaceutics17030342
Verify or expand the search:
- PubMed search for NCT06551415
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Dabigatran Etexilate 150mg
Trials testing the same drug.
- NCT06551402 — Dabigatran Versus Rivaroxaban in Cerebral Venous Thrombosis · Phase 3 · recruiting
- NCT06387407 — Population Pharmacokinetic Study of the Effect of Polymorphisms in the ABCB1 and CES1 Genes on the Pharmacokinetics of D · not yet recruiting
- NCT02348723 — Uninterrupted Dabigatran Etexilate in Comparison to Uninterrupted Warfarin in Pulmonary Vein Ablation (RE-CIRCUIT) · Phase 4 · completed
- NCT02164864 — Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With · Phase 3 · completed
Other recruiting trials for Cerebral Venous Sinus Thrombosis
Currently open trials in the same condition.
- NCT06551402 — Dabigatran Versus Rivaroxaban in Cerebral Venous Thrombosis · Phase 3 · recruiting
Other Kafrelsheikh University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06551415 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Kafrelsheikh University
- Last refreshed: 13 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06551415.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing