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NCT06550232
IV PAPAVERINE Prior to Propess for Labor Induction
Phase 4 trial testing Papaverine in Induced Vaginal Delivery in 110 participants. Completed in 23 March 2025.
23 March 2025
Quick facts
| Lead sponsor | Western Galilee Hospital-Nahariya |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 110 |
| Start date | 12 August 2024 |
| Primary completion | 23 March 2025 |
| Estimated completion | 23 March 2025 |
| Sites | 1 location across Israel |
Drugs / interventions tested
- Papaverine — full drug profile →
- placebo
Conditions studied
- Induced Vaginal Delivery — all drugs for Induced Vaginal Delivery →
Sponsor
Western Galilee Hospital-Nahariya
Who can join
Adults 18 to 45, female only, with Induced Vaginal Delivery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigators aim to evaluate the effect of administering papaverine prior to PGE2 insertion on changes in Bishop-scores and on the induction-to-delivery interval. Researchers will compare drug papaverine to a placebo
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06550232
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Papaverine
Trials testing the same drug.
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- NCT05136846 — Papaverine in Combination With Chemoradiation for the Treatment of Stage II-III Non-small Cell Lung Cancer · Phase 1 · recruiting
- NCT04162834 — Effect of Papaverine on Renal Artery Blood Flow Volume · Phase 4 · completed
- NCT03894904 — Papaverine vs Heparin for Peripheral Arterial Catheter Patency in Pediatric Patients · Phase 4 · completed
Other Western Galilee Hospital-Nahariya trials
Trials by the same sponsor.
- NCT07536425 — Preoperative Indomethacin and Paracetamol for Pain Management During Oocyte Retrieval in IVF Patients · Phase 4 · not yet recruiting
- NCT07353281 — Carbetocin vs Misoprostol for Postpartum Hemorrhage Prevention · NA · not yet recruiting
- NCT07317674 — Combined Nipple Stimulation and Foley Balloon for Cervical Ripening · NA · not yet recruiting
- NCT06578754 — Validation Testing for Plasma Oxalate Levels in the Biochemical Laboratory at the Galilee Medical Center, in Collaborati · not yet recruiting
- NCT07311395 — Local Subcutaneous Gentamicin for Prevention of Surgical Site Infection After Elective Cesarean Section · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06550232 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Western Galilee Hospital-Nahariya
- Last refreshed: 26 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06550232.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing