NCT06548646

Ultrasound-guided Thoracic Interfascial Plane Nerve Block Versus Erector Spinae Plane Block for Pain Control After Modified Radical Mastectomy

Recruiting now NA Last updated 13 January 2025

What this trial tests

NA trial testing Thoracic Interfascial Plane Block in Postoperative Pain Following Modified Radical Mastectomy for Breast Cancer in 50 participants. Currently enrolling.

Timeline

1 November 2024

Primary endpoint
1 March 2025

15 March 2025

Quick facts

Lead sponsor	Safie ramez tewfeik abd el moneim
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	50
Start date	1 November 2024
Primary completion	1 March 2025
Estimated completion	15 March 2025
Sites	1 location across Egypt

Drugs / interventions tested

• Thoracic Interfascial Plane Block — full drug profile →
• Erector Spinae Plane Block — full drug profile →

Conditions studied

• Postoperative Pain Following Modified Radical Mastectomy for Breast Cancer — all drugs for Postoperative Pain Following Modified Radical Mastectomy for Breast Cancer →

Sponsor

Safie ramez tewfeik abd el moneim

Who can join

21 and older, female only, with Postoperative Pain Following Modified Radical Mastectomy for Breast Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study compares two methods of local pain control in patients undergoing Modified Radical Mastectomy, a common surgery for breast cancer( tumor in the breast) treatment. It aims to determine which method, the Thoracic Interfascial Plane Block or the Erector Spinae Plane Block, provides better pain relief after surgery, reduces side effects, and increases patient satisfaction.

Why This Study Is Important:

Breast cancer surgery can cause significant pain, and managing this pain is important for a quick recovery. Currently, pain is often managed with opioids, which can cause side effects like nausea and drowsiness. invistigators want to find a method that controls pain effectively with fewer side effects, helping patients recover faster and feel better.

Who Can Take Part:

Women aged 21 and older who are scheduled for a Modified Radical Mastectomy at Ain Shams University hospitals can participate in this study.

What Will Happen During the Study:

Participants will be randomly assigned to receive either the Thoracic Interfascial Plane Block or the Erector Spinae Plane Block before surgery.

Pain levels will be measured using a numerical pain score from 1 to 10. Researchers will track the amount of pain medication needed, the time it takes to feel pain relief, and any side effects.

Other factors such as sleep quality, time to start walking again, and overall satisfaction with pain control will also be recorded.

What investigators hope to Learn:

Investigators hope to find out which nerve block provides better pain relief after surgery. By comparing TIPB and ESPB, with the aim to identify the method that:

Requires less additional pain medication Has fewer side effects Improves sleep quality and overall recovery Increases patient satisfaction

Significance:

This study could lead to better pain management strategies for breast cancer surgery, reducing the need for opioids and enhancing patient recovery and comfort.

Participation:

Participants will be monitored closely during and after the procedure to ensure their safety and well-being. The results of this study could help improve pain management for future patients undergoing similar surgeries.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.