Last reviewed · How we verify
NCT06548594
Out of State - tAN hEDS
NA trial testing Transcutaneous Auricular Neurostimulation in Hypermobile EDS (hEDS) in 30 participants. Completed in 29 March 2026.
1 April 2026
Quick facts
| Lead sponsor | Medical University of South Carolina |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 27 November 2024 |
| Primary completion | 1 April 2026 |
| Estimated completion | 29 March 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Transcutaneous Auricular Neurostimulation
Conditions studied
- Hypermobile EDS (hEDS) — all drugs for Hypermobile EDS (hEDS) →
Sponsor
Medical University of South Carolina
Who can join
Adults 18 to 65, any sex, with Hypermobile EDS (hEDS). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Hypermobile EDS and hypermobile spectrum disorder (collectively referred to as hEDS) are estimated to affect 1 in 500 individuals worldwide. hEDS patients have limited treatment options for their numerous symptoms that impact the quality of life. This clinical trial tests a new ear stimulation method in hEDS patients to determine if it may improve quality of life.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06548594
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Transcutaneous Auricular Neurostimulation
Trials testing the same drug.
- NCT07517172 — Evaluating Noninvasive Brain Stimulation for TMD Pain: A Feasibility Study · NA · not yet recruiting
- NCT07144436 — Post-stroke Pain tAN-fMRI · NA · recruiting
- NCT06105541 — Hypermobile Ehlers-Danlos Syndrome - Transcutaneous Auricular Neuromodulation · NA · completed
Other Medical University of South Carolina trials
Trials by the same sponsor.
- NCT06491264 — Multiparameter Optimized tES for Memory in Aging · NA · withdrawn
- NCT07513389 — Omission of Postoperative Radiation in HPV-Associated Oropharyngeal Cancer Using ctHPVDNA Surveillance (OPERATION) · Phase 2 · not yet recruiting
- NCT03101917 — Microtable® Method for Cochlear Implantation Investigational Device Exemption (IDE) · NA · not yet recruiting
- NCT07149207 — Intraoperative Molecular Imaging Using ICG for Head and Neck Tumors · Phase 2 · recruiting
- NCT06148038 — CBD for Breast Cancer Primary Tumors · Phase 1 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06548594 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Medical University of South Carolina
- Last refreshed: 27 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06548594.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing