Effect and Safety of Fexofenadine Hydrochloride vs Placebo in Patients With Acute Myocardial Infaction: A Randomized Clinical Trial

NCT06548204 Phase 2 NOT_YET_RECRUITING

The purpose of this study was to evaluate the efficacy and safety of fexofenadine hydrochloride on the basis of standard treatment after PCI in STEMI patients.

Details

Lead sponsor	Second Affiliated Hospital, School of Medicine, Zhejiang University
Phase	Phase 2
Status	NOT_YET_RECRUITING
Enrolment	165
Start date	2024-09
Completion	2026-09

Conditions

• ST-segment Elevation Myocardial Infarction (STEMI)

Interventions

• Fexofenadine Hydrochloride 60mg bid
• Placebo
• Fexofenadine Hydrochloride 120mg bid

Primary outcomes

• Late gadolinium enhancement/Left ventricular mass (LGE/LV%) — 6 months after myocardial infarction
  LGE/LV% will be assessed by CMR