Pioneering and Affordable Strategies to Prevent Progression of Prediabetes, Obesity and CV Risk in Hispanics (Pre-DM)

NCT06446531 Phase 1 RECRUITING

The investigators are studying how to help people with prediabetes (Pre-DM) and obesity. The goal is to use new and affordable treatments to bring blood sugar levels back to normal and help participants to lose weight. The investigators also want to reduce participants risk of heart problems. The study team will look at how these treatments affect metabolism and other body functions to help find new ways to treat diabetes and obesity in the future.

Details

Lead sponsor	The University of Texas Health Science Center at San Antonio
Phase	Phase 1
Status	RECRUITING
Enrolment	64
Start date	2024-09-11
Completion	2027-07

Conditions

• Pre-Diabetes
• Weight, Body
• Cardiovascular Diseases

Interventions

• Placebo
• Rybelsus Tablet
• Jardiance 25Mg Tablet
• Metformin
• Actos

Primary outcomes

• Hemoglobin A1c Level (HBA1c) — Baseline and 6 months
  Percentage of glycated hemoglobin level in blood

Countries

United States