Efficacy and Safety of Lactoferrin in Heart Failure Patients

NCT06427200 Phase 4 NOT_YET_RECRUITING

This study will be conducted to determine the efficacy and safety of lactoferrin versus oral iron versus lactoferrin plus oral iron as an add on therapy in reduced ejection fraction heart failure patients with iron deficiency. •Patients will be randomly distributed into the three groups * All patients will be subjected to baseline data assessment * Follow up after 12 weeks

Details

Lead sponsor	Cairo University
Phase	Phase 4
Status	NOT_YET_RECRUITING
Enrolment	114
Start date	2024-07
Completion	2027-07

Conditions

• Heart Failure With Reduced Ejection Fraction

Interventions

• oral Iron
• Lactoferrin
• lactoferrin and oral iron

Primary outcomes

• Change in health-related quality of life (HR-QoL) — 3 months
  • Change in health-related quality of life (HR-QoL) as evaluated by Minnesota Living with Heart Failure Questionnaire (MLHFQ) minimum score:0 maximum score:105 minimum score is a better outcome