Last reviewed · How we verify
NCT06378632: DETECT-HF
AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM
trial testing Hearo App in Heart Failure in 500 participants. Currently enrolling.
1 July 2025
Quick facts
| Lead sponsor | Cordio Medical |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 500 |
| Start date | 11 February 2022 |
| Primary completion | 1 July 2025 |
| Estimated completion | 15 July 2025 |
| Sites | 45 locations across United States, Israel, Spain |
Drugs / interventions tested
- Hearo App
Conditions studied
- Heart Failure — all drugs for Heart Failure →
Sponsor
Cordio Medical
Who can join
22 and older, any sex, with Heart Failure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Study Design: This is an international, multicenter, observational, non-interventional, prospective, blinded, single-arm, two-period study, to collect patient utterances that will be retrospectively analyzed to determine the sensitivity and UPNR of the HearO system.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Remote monitoring in heart failure: artificial intelligence and the use of remote speech analysis to detect worsening heart failure events.
Abraham JD, Abraham WT. · · 2025 · cited 2× · PMID 40425974 · DOI 10.1007/s10741-025-10522-1 -
Invasive and Non-Invasive Remote Patient Monitoring Devices for Heart Failure: A Comparative Review of Technical Maturity and Clinical Readiness.
Luque I, Gadea M, Comas A, Becerra-Fajardo L, et al · · 2025 · cited 1× · PMID 41157505 · DOI 10.3390/s25206453
Verify or expand the search:
- PubMed search for NCT06378632
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Heart Failure
Currently open trials in the same condition.
- NCT06118983 — Improving TRansitions ANd OutcomeS for Heart FailurE Patients in Home Health CaRe (I-TRANSFER-HF) · NA · recruiting
- NCT07496372 — Efficacy and Safety of Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Injection (HiCM-188) in Advanced Heart · Phase 3 · recruiting
- NCT07527156 — Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure · Phase 4 · recruiting
- NCT07263035 — Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart Failure · Phase 4 · recruiting
- NCT07531966 — Vascular Complications After Kidney Transplantation · recruiting
Other Cordio Medical trials
Trials by the same sponsor.
- NCT05876533 — R&D Study to Evaluate Cordio's Usability and to Collect Patient Speech Utterances · active not recruiting
- NCT04325048 — Clinical Evaluation of Cordio Application in Adult COVID-19 Virus Positive Patients · completed
- NCT03714126 — Remote Speech Analysis in HF Patients Undergoing Haemodialysis · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06378632 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cordio Medical
- Last refreshed: 26 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06378632.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing