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NCT06377007: ORION
Refractive Outcomes and Ocular Biometry of Two Swept-Source Optical Coherence Tomography-Based Biometers With Segmental or Equivalent Refractive Indices (ORION)
NA trial testing IOLMaster 700 (Carl Zeiss Meditec AG) in Cataract in 142 participants. Currently enrolling.
30 July 2025
Quick facts
| Lead sponsor | Walailak University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | other |
| Enrollment | 142 |
| Start date | 1 January 2024 |
| Primary completion | 30 July 2025 |
| Estimated completion | 30 December 2025 |
| Sites | 1 location across Thailand |
Drugs / interventions tested
- IOLMaster 700 (Carl Zeiss Meditec AG)
- Argos (Alcon Laboratories, Inc.)
Conditions studied
- Cataract — all drugs for Cataract →
Sponsor
Walailak University
Who can join
Adults 50 to 85, any sex, with Cataract. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Cataract surgery represents a common surgical intervention, encompassing the extraction of the opaque natural crystalline lens, followed by the substitution with an artificial intraocular lens (IOL). To ascertain an IOL possessing optimal power, antecedent to the surgery, preoperative evaluations are conducted through the utilization of a biometric devices. Diverse categories of these instruments are accessible, each harnessing distinct optical methodologies or mathematical algorithms to ascertain the most fitting IOL power. The principal objective of this study was to evaluate the ocular biometry and the predictive precision outcome of a biometer that uses standard keratometry to the prediction accuracy of another biometer that uses Total Keratometry.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Refractive prediction accuracy of two swept-source OCT biometers using segmental versus equivalent refractive indices: a randomized clinical study in a Thai cataract surgery cohort
Juhong J, Udomwech L, Rattanasuwan A, Kowanz DH, et al · · 2026 · DOI 10.21203/rs.3.rs-9640650/v1
Verify or expand the search:
- PubMed search for NCT06377007
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Walailak University trials
Trials by the same sponsor.
- NCT06433284 — Comparative Study of Decellularized Human Amniotic Membrane Hydrogel and Inverted Internal Limiting Membrane Flap in Idi · NA · enrolling by invitation
- NCT07470060 — Effects of Core Stability Training Using Pilates on Core Muscle Strength, Pulmonary Function, and Cardio-respiratory Fit · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06377007 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Walailak University
- Last refreshed: 26 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06377007.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing