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NCT06376994: Clean Air
Multi-Center Clean Air Randomized Controlled Trial in COPD
Phase 3 trial testing Air cleaner in Chronic Obstructive Pulmonary Disease (COPD) in 770 participants. Currently enrolling.
31 August 2029
Quick facts
| Lead sponsor | JHSPH Center for Clinical Trials |
|---|---|
| Phase | Phase 3 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | prevention |
| Enrollment | 770 |
| Start date | 24 May 2024 |
| Primary completion | 31 August 2029 |
| Estimated completion | 30 November 2029 |
| Sites | 11 locations across United States |
Drugs / interventions tested
- Air cleaner
- Sham air cleaner
Conditions studied
- Chronic Obstructive Pulmonary Disease (COPD) — all drugs for Chronic Obstructive Pulmonary Disease (COPD) →
Sponsor
JHSPH Center for Clinical Trials
Who can join
40 and older, any sex, with Chronic Obstructive Pulmonary Disease (COPD). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a multi-center randomized, sham-controlled clinical trial to determine the effectiveness of an air cleaner intervention aimed at improving indoor air quality on reducing COPD exacerbation risk and improving quality of life, functional status, rescue medication use.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06376994
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Air cleaner
Trials testing the same drug.
- NCT05913765 — Air Filtration for COPD in VA Population of Veterans · NA · active not recruiting
Other recruiting trials for Chronic Obstructive Pulmonary Disease (COPD)
Currently open trials in the same condition.
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- NCT06892210 — Comparing Hydrocortisone and Prednisolone for Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD) · Phase 4 · recruiting
- NCT07477600 — cfMSC Stem Cell Therapy Targeting COPD · Phase 1, PHASE2 · recruiting
- NCT07519603 — Frailty in Older Adults With Chronic Obstructive Pulmonary Disease (COPD) and Outcomes of the VIVIFRAIL Program · NA · recruiting
Other JHSPH Center for Clinical Trials trials
Trials by the same sponsor.
- NCT06272045 — Early Intervention to Promote Cardiovascular Health of Mothers and Children · NA · recruiting
- NCT04551807 — Natural Versus Programmed Frozen Embryo Transfer (NatPro) · Phase 3 · active not recruiting
- NCT03828019 — Adalimumab vs. Conventional Immunosuppression for Uveitis Trial · Phase 3 · completed
- NCT02696564 — Losartan Effects on Emphysema Progression · Phase 4 · completed
- NCT02623426 — Macular Edema Ranibizumab v. Intravitreal Anti-inflammatory Therapy Trial · Phase 3 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06376994 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by JHSPH Center for Clinical Trials
- Last refreshed: 10 October 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06376994.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing