NCT06371664 is a EARLY_PHASE1 clinical trial of Conventional Tray (1 mm) in Gingival Inflammation, sponsored by University of Santiago de Compostela.

Who is sponsoring NCT06371664?

NCT06371664 is sponsored by University of Santiago de Compostela.

What drugs are being tested in NCT06371664?

Interventions in NCT06371664: Conventional Tray (1 mm), Extended Tray (3 mm).

What condition does NCT06371664 study?

NCT06371664 studies Gingival Inflammation.

Is NCT06371664 still recruiting?

NCT06371664 is currently completed. Last updated 17 April 2024.

Last reviewed 2024-04-17 · How we verify

NCT06371664

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Gingival Irritation Due to Bleaching Tray Design in an At-home Bleaching Treatment

Completed EARLY_PHASE1 Last updated 17 April 2024

What this trial tests

EARLY_PHASE1 trial testing Conventional Tray (1 mm) in Gingival Inflammation in 72 participants. Completed in 5 April 2023.

Timeline

1 March 2023

Primary endpoint
5 April 2023

5 April 2023

Quick facts

Lead sponsor	University of Santiago de Compostela
Phase	EARLY_PHASE1
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	prevention
Enrollment	72
Start date	1 March 2023
Primary completion	5 April 2023
Estimated completion	5 April 2023
Sites	1 location across Spain

Drugs / interventions tested

Conventional Tray (1 mm) — full drug profile →
Extended Tray (3 mm) — full drug profile →

Conditions studied

Gingival Inflammation — all drugs for Gingival Inflammation →

Sponsor

University of Santiago de Compostela

Who can join

18 and older, any sex, with Gingival Inflammation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The primary aim of this study is to assess whether the design of the bleaching tray used in at-home bleaching treatment is directly correlated with the risk of gingival irritation. Additionally, it aims to investigate whether the design influences the likelihood of dental sensitivity and its impact on the degree of tooth whitening.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Does the use of a 3-mm extended tray during an at-home bleaching treatment increase gingival irritation? A randomized clinical trial.
Pereira-Lores P, Martín-González J, Gancedo-Gancedo T, Alonso de la Peña V, et al · · 2025 · cited 2× · PMID 39562219 · DOI 10.1016/j.prosdent.2024.09.029
12th CONSEURO and the 25th National and 12th International SEOC Congress, April 3-5, 2025, Cordoba, Spain.
· 2025 · PMID 41431710 · DOI 10.4317/jced.1122335667806

Verify or expand the search:

Other recruiting trials for Gingival Inflammation

Currently open trials in the same condition.

NCT07104019 — Biofiller and Gingival Phenotype Thickening · NA · recruiting
NCT07100574 — Bacteria in Dental Plaque and Atheroma Plaque · recruiting
NCT06752291 — EFFECTIVENESS of WATER FLOSS in PLAQUE REMOVAL and PREVENTION of WHITE SPOT LESIONS in ORTHODONTIC PATIENTS: a RANDOMISE · NA · active not recruiting

Other University of Santiago de Compostela trials

Trials by the same sponsor.

NCT07466004 — PERMA-Based Mobile Psychological Intervention With and Without Telephone Support for University Students · NA · not yet recruiting
NCT07343284 — Nursing Health Education to Improve Functionality and Quality of Life After Ischemic Stroke · NA · not yet recruiting
NCT07430748 — REGENFAST vs L-PRF in Periodontal Regeneration · EARLY_PHASE1 · active not recruiting
NCT07355673 — The Influence of Isolation Techniques in Gingival Irritation During an In-office Bleaching · NA · completed
NCT07355647 — Efficacy of a Desensitizing Agent During In-Office Bleaching · EARLY_PHASE1 · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06371664 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Santiago de Compostela
Last refreshed: 17 April 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06371664.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing