A Prospective, Randomized, Parallel, Single-blind Clinical Study of the Effectiveness, Tolerability and Safety of the Drug "Anti-spike, Gel, 100 g in Bottles in Package No. 1" Produced by the Republican Unitary Enterprise "Unitekhprom BSU", Belarus, With a Single Intraperitoneal Use After Surgical Interventions in Adult Patients With Acute Phlegmonous Appendicitis (OLTOSPAN-02)

NCT06365632 Phase 2 ACTIVE_NOT_RECRUITING

The purpose of the clinical trials is the evaluation of the effectiveness and safety of a single intraperitoneal use of the drug "Antispike, gel, 100 g in a bottle" produced by Unitary Enterprise Unitehprom BSU, Belarus in patients after surgical control of acute phlegmonous appendicitis to prevent abdominal adhesions.

Details

Lead sponsor	Research Institute for Physical Chemical Problems of the Belarusian State University
Phase	Phase 2
Status	ACTIVE_NOT_RECRUITING
Enrolment	100
Start date	2025-03-19
Completion	2025-12

Conditions

• Abdominal Adhesions

Interventions

• Antispike gel, 100 g in a flask, produced by UNITEHPROM BSU, Republic of Belarus
• antegrade appendectomy

Primary outcomes

• Number of patients with acute phlegmonous appendicitis cured — from surgery to 3 weeks
  Number of patients cured

Countries

Belarus