Last reviewed · How we verify
NCT06363058
Electrical Stimulation Cycling Training Effects on SCA
NA trial testing ES Cycling Training in Spinocerebellar Ataxia (SCA) in 145 participants. Currently enrolling.
31 July 2025
Quick facts
| Lead sponsor | Chang Gung University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | other |
| Enrollment | 145 |
| Start date | 8 April 2022 |
| Primary completion | 31 July 2025 |
| Estimated completion | 31 July 2025 |
| Sites | 1 location across Taiwan |
Drugs / interventions tested
- ES Cycling Training
Conditions studied
- Spinocerebellar Ataxia (SCA) — all drugs for Spinocerebellar Ataxia (SCA) →
Sponsor
Chang Gung University
Who can join
20 and older, any sex, with Spinocerebellar Ataxia (SCA). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To focuses on the challenges faced by individuals with spinocerebellar ataxia (SCA), highlighting the major clinical sign of ataxia that affects their stability and ability to perform daily activities, thereby impacting their quality of life. It outlines the concept of neural plasticity, which is the brain's ability to adapt through changes in excitability, and notes that these changes are more enduring in the central nervous system (CNS) than in the peripheral nervous system (PNS). This adaptability, crucial for memory and motor learning, is compromised in SCA patients due to impaired brain areas and pathways. The summary further delves into motor learning, distinguishing between explicit and implicit learning, and points out that SCA patients exhibit deficiencies in procedural learning and cerebellar function. It also introduces the concept of priming as a preparatory mechanism that can enhance the effectiveness of physical therapy by modifying subsequent responses to stimuli. The document suggests that cycling, as an aerobic exercise, could prime the brain for improved blood flow and oxygenation, thereby supporting synaptic plasticity and the release of beneficial neurotrophic factors. Finally, the project aims to deepen the understanding of motor performance and learning mechanisms in SCA patients and apply these insights to clinical rehabilitation strategies.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06363058
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Chang Gung University trials
Trials by the same sponsor.
- NCT07465770 — Optimizing Medical Decisions and Care for Adult Orphans · NA · enrolling by invitation
- NCT07112729 — Effectiveness of SMS Invitation on Colorectal Cancer Screening on 45-49-Year-Olds · NA · completed
- NCT05953948 — Effectiveness of Intelligent Case Manage Platform in Liver Transplant Recipients · NA · enrolling by invitation
- NCT06464640 — Efficacy of the "Living With Type 1 Diabetes to Grown-Up" Interactive Podcast Program · NA · not yet recruiting
- NCT06392945 — Effects of Rhythmic Auditory Cueing Augments Cognitive Treadmill Walking Training in Individuals With Chronic Stroke · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06363058 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Chang Gung University
- Last refreshed: 17 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06363058.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing