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NCT06357481: Endodontics
Evaluation of Postoperative Pain After Single Visit Retreatment of Symptomatic and Asymptomatic Teeth
NA trial testing Endodontic Retreatment in Post-operative Pain in 80 participants. Completed in 28 January 2024.
30 January 2023
Quick facts
| Lead sponsor | Saglik Bilimleri Universitesi |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 80 |
| Start date | 26 January 2023 |
| Primary completion | 30 January 2023 |
| Estimated completion | 28 January 2024 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Endodontic Retreatment
Conditions studied
- Post-operative Pain — all drugs for Post-operative Pain →
- Retreatment — all drugs for Retreatment →
- Symptomatic Periapical Periodontitis — all drugs for Symptomatic Periapical Periodontitis →
- Endodontic Disease — all drugs for Endodontic Disease →
Sponsor
Saglik Bilimleri Universitesi — full company profile →
Who can join
Adults 18 to 67, any sex, with Post-operative Pain or Retreatment. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Introduction: The aim of this study comparing the post operative pain after the retreatment of asymptomatic and symptomatic teeth that during single visit treatment with rotary and reciprocal nickel titanium files. Methods: One hundred and forty one patients scheduled for non-surgical endodontic retreatment were included for evaluation. Eighty five patients who needed endodontic retreatment were assingned to 2 groups according to semptomatic or asemptomatic teeth and 4 subgroups with rotary and resiprocal files. Endodontic filling material was removed with One Flare and MicroMega REMOVER files in the retreatment kit. Patients then recorded their postoperative pain on a VAS scale at 24h, 48h, 72h, 7 days and 14 days post-treatment. Results were analyzed using the Shapiro-Wilk, Mann-Whitney U, Kruskal-Wallis, Dunn-Bonferroni and Pearson Chi-square tests.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Postoperative Pain Following Single-Visit Nonsurgical Retreatment Using Minimally Invasive Rotary vs. Reciprocating Nickel-Titanium File Systems: A Two-Arm Parallel Randomized Clinical Trial.
Güneç HG, Pehlivan B, Topbaş C, Kul AK, et al · · 2025 · PMID 40958962 · DOI 10.1155/prm/6826535
Verify or expand the search:
- PubMed search for NCT06357481
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06357481 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Saglik Bilimleri Universitesi
- Last refreshed: 17 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06357481.
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