Last reviewed · How we verify
NCT06356233: FIMBEX
Phenotyping and Identification of Biological Markers in STXBP1 Encephalopathy
trial testing No intervention will be performed in STXBP1 Encephalopathy With Epilepsy in 10 participants. Not yet recruiting.
1 October 2027
Quick facts
| Lead sponsor | Fundación Iniciativa para las Neurociencias (FINCE) |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 10 |
| Start date | 1 May 2024 |
| Primary completion | 1 October 2027 |
| Estimated completion | 31 December 2027 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- No intervention will be performed
Conditions studied
- STXBP1 Encephalopathy With Epilepsy — all drugs for STXBP1 Encephalopathy With Epilepsy →
Sponsor
Fundación Iniciativa para las Neurociencias (FINCE)
Who can join
Adults 1 Month to 10, any sex, with STXBP1 Encephalopathy With Epilepsy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a prospective observational study to evaluate the phenotype of 10 patients under 10 years of age with developmental epileptic encephalopathy due to mutation of the STXBP1 gene. The study will consist of a clinical and neurodevelopmental evaluation, magnetic resonance imaging, prolonged electroencephalogram, cardiological study, and analysis of biomarkers in cerebrospinal fluid. These patients will be followed up for 3 years. The aim of the study is, knowing the baseline phenotype, to analyse the response to commonly used drugs and to anticipate the response to different drugs available on the market in this group of patients based on clinical and biomarker assessment (EEG, MRI and study of specific proteins and neurotransmitters in plasma, urine and CSF).
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06356233
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of No intervention will be performed
Trials testing the same drug.
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Other recruiting trials for STXBP1 Encephalopathy With Epilepsy
Currently open trials in the same condition.
- NCT06625112 — A Multicentric European Study to Promote Clinical Trial Readiness for STXBP1-related Disorders · recruiting
- NCT06555965 — STXBP1 and SYNGAP1 Related Disorders Natural History Study · recruiting
- NCT05161494 — Gait in Rare Diseases · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06356233 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fundación Iniciativa para las Neurociencias (FINCE)
- Last refreshed: 10 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06356233.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing