Who is sponsoring NCT06355063?

NCT06355063 is sponsored by Pulse Biosciences, Inc..

What drugs are being tested in NCT06355063?

Interventions in NCT06355063: CellFX® nsPFA™ Cardiac Surgery System.

What condition does NCT06355063 study?

NCT06355063 studies Atrial Fibrillation, Surgery, Ablation of Atrial Fibrillation, Clamp Study.

Is NCT06355063 still recruiting?

NCT06355063 is currently recruiting now. Last updated 12 January 2026.

Last reviewed 2026-01-12 · How we verify

NCT06355063

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

CellFX® nsPFA™ Cardiac Surgery System to Treat Atrial Fibrillation

Recruiting now NA Last updated 12 January 2026

What this trial tests

NA trial testing CellFX® nsPFA™ Cardiac Surgery System in Atrial Fibrillation in 30 participants. Currently enrolling.

Timeline

31 July 2024

Primary endpoint
31 December 2026

31 December 2027

Quick facts

Lead sponsor	Pulse Biosciences, Inc.
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	30
Start date	31 July 2024
Primary completion	31 December 2026
Estimated completion	31 December 2027
Sites	6 locations across Austria, Netherlands, Poland

Drugs / interventions tested

CellFX® nsPFA™ Cardiac Surgery System

Conditions studied

Atrial Fibrillation — all drugs for Atrial Fibrillation →
Surgery — all drugs for Surgery →
Ablation of Atrial Fibrillation — all drugs for Ablation of Atrial Fibrillation →
Clamp Study — all drugs for Clamp Study →

Sponsor

Pulse Biosciences, Inc.

Who can join

Adults 18 to 85, any sex, with Atrial Fibrillation or Surgery. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This feasibility study will be conducted to demonstrate the initial safety and effectiveness of the CellFX® nsPFA™ Cardiac Clamp in performing a box lesion around the 4 pulmonary veins as an isolated procedure or as a part of a more extensive surgical ablation set in conjunction with concomitant cardiac surgical procedure.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Impact of pulse duration on cardiac electroporation: nanosecond pulses enhance cardiomyocyte selectivity and promote a Raman-detected shift towards apoptotic cell death.
Sowa PW, Mariyanats A, Kiełbik A, Rohlfing AK, et al · · 2025 · cited 1× · PMID 40971515 · DOI 10.1093/europace/euaf217

Verify or expand the search:

Other recruiting trials for Atrial Fibrillation

Currently open trials in the same condition.

NCT07429214 — A Study of VARIPULSE Catheter and TRUPULSE Generator With VARIPULSE Pro Software in Participants With PAF or PsAF · NA · recruiting
NCT07271238 — Feasibility Study on the VERAFEYE Imaging and Navigation System for Guided Catheter Ablation Procedures · NA · recruiting
NCT07388108 — Atrial Dyssynchrony to Predict Arrhythmias in the Postoperative Setting of Cardiovascular Surgery. · recruiting
NCT07428967 — AV Node Ablation and CONDUCTion System Pacing for Atrial Fibrillation With Preserved Left Ventricular Function · NA · recruiting
NCT06650995 — AlEX-DHF: Ablation and Exercise in Diastolic Heart Failure · NA · recruiting

Other Pulse Biosciences, Inc. trials

Trials by the same sponsor.

NCT07287176 — Prospective Evaluation of the Pulse Biosciences nPulse™ Vybrance™ Percutaneous Electrode System · NA · recruiting
NCT06696170 — CellFX® Nanosecond Pulsed Field Ablation (PFA) 360 Catheter Ablation System for Treatment of Atrial Fibrillation · NA · recruiting
NCT06117085 — CellFX ® Percutaneous Electrode (PE) Treatment of Symptomatic Benign Thyroid Nodules · NA · completed
NCT04918381 — CellFX Treat & Resect Low-Risk BCC Feasibility Study · NA · completed
NCT04738734 — CellFX Comparison to Cryosurgery in Cutaneous Non-Genital Common Warts · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06355063 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Pulse Biosciences, Inc.
Last refreshed: 12 January 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06355063.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing