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NCT06354361: TI-GMT
Trauma-Informed Goal Management Training for Individuals With Post-traumatic Stress Disorder (PTSD)
NA trial testing Trauma-Informed Goal Management Training (TI-GMT) in Post-Traumatic Stress Disorder in 33 participants. Completed in 3 November 2025.
3 October 2025
Quick facts
| Lead sponsor | McMaster University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 33 |
| Start date | 10 August 2024 |
| Primary completion | 3 October 2025 |
| Estimated completion | 3 November 2025 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Trauma-Informed Goal Management Training (TI-GMT)
Conditions studied
- Post-Traumatic Stress Disorder — all drugs for Post-Traumatic Stress Disorder →
Sponsor
McMaster University
Who can join
Adults 18 to 65, any sex, with Post-Traumatic Stress Disorder. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Goal Management Training (GMT) is a program designed to help improve cognitive functioning. For this study, researchers have worked closely with the developers of this program to create a modified version called Trauma-Informed Goal Management Training (TI-GMT), that is more sensitive to the needs of individuals experiencing symptoms of posttraumatic stress and posttraumatic stress disorder (PTSD). The goal of this clinical trial is to find out whether this modified, Trauma-Informed Goal Management Training program is effective for individuals experiencing symptoms associated with Post-Traumatic Stress Disorder. The main questions it aims to answer are: 1. Does Trauma-Informed Goal Management Training result in improved neuropsychological functioning and reductions in the severity of PTSD symptoms from baseline to post? 2. Does Trauma-Informed Goal Management Training result in self-reported improvements in cognitive functioning and the overall ability to function (including intent to return to work, and/or intent to stay at work, reductions in disability status, etc.) from baseline to post? 3. Does Trauma-Informed Goal Management Training continue to benefit individuals three months after treatment? Participants will: * complete three separate assessments before starting the treatment - a clinical interview to evaluate symptoms, a cognitive assessment, and completing a set of questionnaires * participate in a nine-week group treatment program (one day a week for two hours) * complete four separate assessments after completing the treatment - a clinical interview to evaluate symptoms, a cognitive assessment, a feedback interview, and completing a set of questionnaires * complete three separate assessments three months after completing the treatment - a clinical interview to evaluate symptoms, a cognitive assessment, and completing a set of questionnaires
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06354361
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other McMaster University trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06354361 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by McMaster University
- Last refreshed: 13 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06354361.
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