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NCT06353620
Structural-functional Connectome in Drug-resistant Epilepsies and Neurodevelopmental Syndromes With Epilepsy
trial testing High Density EEG recording in Epilepsy in 120 participants. Currently enrolling.
18 March 2024
Quick facts
| Lead sponsor | IRCCS Eugenio Medea |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 120 |
| Start date | 13 February 2024 |
| Primary completion | 18 March 2024 |
| Estimated completion | 28 February 2027 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- High Density EEG recording
- Rey Complex Figure Test
Conditions studied
- Epilepsy — all drugs for Epilepsy →
- Angelman Syndrome — all drugs for Angelman Syndrome →
- Dup15q Syndrome — all drugs for Dup15q Syndrome →
Sponsor
IRCCS Eugenio Medea — full company profile →
Who can join
Adults 6 to 75, any sex, with Epilepsy or Angelman Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Recent studies have shown that the aperiodic part of the signal (neuronal avalanches) of electroencephalography (EEG) contains important information about the dynamics of neuronal networks. Indeed, this has helped to identify functionally altered areas in patients with temporal epilepsy by simply using the resting EEG signal. Furthermore, it has been seen that the propagation of neuronal avalanches (VNs) correlates with the morphological organization of the cerebral cortex. Therefore, NAs represent a measure with direct utility for studying functional reorganization pre and post drug/surgical treatment. In addition, the aperiodic portion of the signal may represent a noninvasive measure of the excitation/inhibition relationship, which is known of being altered both in epilepsy and in some rare neurodevelopmental syndromes (example: Angelman and Dup15q)
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06353620
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
Other recruiting trials for Epilepsy
Currently open trials in the same condition.
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- NCT07219407 — A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures · Phase 2 · recruiting
- NCT07417280 — LIFUS For Neurological Disorders · NA · recruiting
- NCT07490769 — Levetiracetam Three Times Daily in Epilepsy · Phase 3 · recruiting
Other IRCCS Eugenio Medea trials
Trials by the same sponsor.
- NCT07095062 — Electroencephalogram in Patients With Friedreich's Ataxia for the Study of the Structural and Functional Connectome. · NA · recruiting
- NCT06993389 — AI-based Model for Rehabilitation Engagement and Motor Performance Evaluation in Pediatric Patients · recruiting
- NCT06999850 — Implementation and Validation of Instrumented Stair Climb Test · NA · recruiting
- NCT06666777 — Speech Therapy and Parenting for Early Socio-communicAtive sKills · NA · recruiting
- NCT07470138 — Sleep Disturbance in Subjects With Autism Spectrum Disorders (ASD) in Preschool Age (18-60 Months) · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06353620 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by IRCCS Eugenio Medea
- Last refreshed: 9 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06353620.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing