Who is sponsoring NCT06350864?

NCT06350864 is sponsored by Ain Shams University.

What drugs are being tested in NCT06350864?

Interventions in NCT06350864: High-flow nasal cannula (HFNC), Conventional nasal oxygen therapy (COT), Upper gastrointestinal endoscopy (UGE) including gastroscopy, Upper gastrointestinal endoscopy (UGE) including Endoscopic ultrasound (EUA).

What condition does NCT06350864 study?

NCT06350864 studies Upper Gastrointestinal Bleeding.

Is NCT06350864 still recruiting?

NCT06350864 is currently completed. Last updated 29 October 2024.

Last reviewed 2024-10-29 · How we verify

NCT06350864

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

HFNC Versus Conventional Oxygen Therapy in Prolonged Upper Gastrointestinal Endoscopy in the ICU

Completed NA Last updated 29 October 2024

What this trial tests

NA trial testing High-flow nasal cannula (HFNC) in Upper Gastrointestinal Bleeding in 70 participants. Completed in 20 September 2024.

Timeline

10 April 2024

Primary endpoint
1 September 2024

20 September 2024

Quick facts

Lead sponsor	Ain Shams University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	70
Start date	10 April 2024
Primary completion	1 September 2024
Estimated completion	20 September 2024
Sites	1 location across Egypt

Drugs / interventions tested

High-flow nasal cannula (HFNC)
Conventional nasal oxygen therapy (COT)
Upper gastrointestinal endoscopy (UGE) including gastroscopy
Upper gastrointestinal endoscopy (UGE) including Endoscopic ultrasound (EUA)

Conditions studied

Upper Gastrointestinal Bleeding — all drugs for Upper Gastrointestinal Bleeding →

Sponsor

Ain Shams University

Who can join

Adults 20 to 60, any sex, with Upper Gastrointestinal Bleeding. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Conventional supplemental oxygen therapy (COT) during upper gastrointestinal (UGI) endoscopy via nasal catheter is considered the standard practice in maintenance of oxygenation and prevention of hypoxia. However, it is still unclear if this oxygen delivery method is optimal in a prolonged (more than 15 minutes) procedure in patients admitted to the ICU. Because of shortage of data in this concern, this prospective, randomized, controlled clinical trial study will aim to evaluate and compare the efficacy of high-flow nasal cannula (HFNC) oxygen therapy versus COT in patients who will undergo prolonged either diagnostic or therapeutic UGI endoscopy in the intensive care unit (ICU) .

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Oxygen therapy in the intensive care unit.
Wang P, Huang Q, Liu B, Xu Q, et al · · 2025 · PMID 40300883 · DOI 10.4103/mgr.medgasres-d-24-00143
HFNC Oxygen Therapy vs COT in Prolonged Upper Gastrointestinal Endoscopy Inside the ICU: A Prospective, Randomized, Controlled Clinical Study.
Mohamed AM, Selima WZ. · · 2025 · PMID 40110237 · DOI 10.5005/jp-journals-10071-24919

Verify or expand the search:

Other trials of High-flow nasal cannula (HFNC)

Trials testing the same drug.

NCT04245241 — Effects of High-Flow Nasal Cannula Therapy Assessed by Electrical Impedance Tomography · completed

Other recruiting trials for Upper Gastrointestinal Bleeding

Currently open trials in the same condition.

NCT04902248 — OTSC vs. Angiographic Embolization in Patients With Refractory Non-variceal Upper Gastrointestinal Bleeding · NA · recruiting

Other Ain Shams University trials

Trials by the same sponsor.

NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06350864 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
Last refreshed: 29 October 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06350864.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing