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NCT06348953
Bioactive Versus Non-Bioactive Restorative System in Deep Carious Molars
NA trial testing selective caries removal and conventional non-bioactive restorative system in Dental Caries in 50 participants. Completed in 10 December 2025.
10 December 2025
Quick facts
| Lead sponsor | Cairo University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 50 |
| Start date | 1 June 2024 |
| Primary completion | 10 December 2025 |
| Estimated completion | 10 December 2025 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- selective caries removal and conventional non-bioactive restorative system
- selective caries removal and bioactive restorative system
Conditions studied
- Dental Caries — all drugs for Dental Caries →
- Dental Diseases — all drugs for Dental Diseases →
- Deep Caries — all drugs for Deep Caries →
- Tooth Diseases — all drugs for Tooth Diseases →
Sponsor
Cairo University
Who can join
Adults 18 to 40, any sex, with Dental Caries or Dental Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This research study delves into the effectiveness of bioactive and non-bioactive restorative systems in deep carious permanent molars treated with selective caries removal. Selective caries removal techniques aim to preserve as much healthy tooth structure as possible while effectively eliminating carious tissue. The study investigates how the choice of restorative material influences the outcomes of selective caries removal procedures in deep carious lesions. By assessing factors such as restoration integrity, pulpal response, and long-term success rates, the research seeks to provide evidence-based insights into the comparative performance of bioactive and non-bioactive restorative systems in this clinical context.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06348953
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Cairo University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06348953 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cairo University
- Last refreshed: 18 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06348953.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing