Last reviewed · How we verify

NCT06336382

Tau Biomarkers in Late-onset Psychosis (LOP)

Recruiting now Last updated 29 September 2025
What this trial tests

trial testing Tau PET imaging scan in Late Onset Schizophrenia in 16 participants. Currently enrolling.

Timeline
16 February 2024
Primary endpoint
31 December 2026
30 June 2027

Quick facts

Lead sponsorJeremy Koppel
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment16
Start date16 February 2024
Primary completion31 December 2026
Estimated completion30 June 2027
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

Jeremy Koppel

Who can join

Adults 65 to 85, any sex, with Late Onset Schizophrenia or Delusional Disorder (Late Onset). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Hallucinations or delusions that occur for the first time in older people with no acute medical problems or mood symptoms may be related to impending dementia. This study aims to confirm this hypothesis using novel blood biomarkers and Positron Emission Tomography (PET) imaging tracers, as well as non-invasive testing.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Revisiting the therapeutic landscape of tauopathies: assessing the current pipeline and clinical trials.
    Harris GA, Hirschfeld LR, Gonzalez MI, Pritchard MC, et al · · 2025 · cited 8× · PMID 40462159 · DOI 10.1186/s13195-025-01775-x

Verify or expand the search:

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06336382.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing