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NCT06336382
Tau Biomarkers in Late-onset Psychosis (LOP)
trial testing Tau PET imaging scan in Late Onset Schizophrenia in 16 participants. Currently enrolling.
31 December 2026
Quick facts
| Lead sponsor | Jeremy Koppel |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 16 |
| Start date | 16 February 2024 |
| Primary completion | 31 December 2026 |
| Estimated completion | 30 June 2027 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Tau PET imaging scan
Conditions studied
- Late Onset Schizophrenia — all drugs for Late Onset Schizophrenia →
- Delusional Disorder (Late Onset) — all drugs for Delusional Disorder (Late Onset) →
Sponsor
Jeremy Koppel
Who can join
Adults 65 to 85, any sex, with Late Onset Schizophrenia or Delusional Disorder (Late Onset). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Hallucinations or delusions that occur for the first time in older people with no acute medical problems or mood symptoms may be related to impending dementia. This study aims to confirm this hypothesis using novel blood biomarkers and Positron Emission Tomography (PET) imaging tracers, as well as non-invasive testing.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Revisiting the therapeutic landscape of tauopathies: assessing the current pipeline and clinical trials.
Harris GA, Hirschfeld LR, Gonzalez MI, Pritchard MC, et al · · 2025 · cited 8× · PMID 40462159 · DOI 10.1186/s13195-025-01775-x
Verify or expand the search:
- PubMed search for NCT06336382
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06336382 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Jeremy Koppel
- Last refreshed: 29 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06336382.
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