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NCT06335420: Px7
Prophylactic Properties of Carrot Juice in Patients With High-Risk Colorectal Polyps
NA trial testing Carrot juice from Yellowstone carrots cultivars in Colorectal Cancer Prevention in 400 participants. Currently enrolling.
1 June 2027
Quick facts
| Lead sponsor | Odense University Hospital |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | prevention |
| Enrollment | 400 |
| Start date | 20 June 2024 |
| Primary completion | 1 June 2027 |
| Estimated completion | 1 December 2027 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Carrot juice from Yellowstone carrots cultivars
- Placebo juice — full drug profile →
Conditions studied
- Colorectal Cancer Prevention — all drugs for Colorectal Cancer Prevention →
Sponsor
Odense University Hospital
Who can join
18 and older, any sex, with Colorectal Cancer Prevention. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this prospective randomized double-blinded bi-national study is to test the prophylactic effect of polyacetylenes from carrots on the population of patients who had a resection of high-risk adenomas of the large bowel. The main question it aims to answer is: Will carrot juice rich in polyacetylenes inhibit neoplastic transformation and growth in high-risk humans? Participants will have to drink 100 ml of juice daily after the adenoma resection for 1 year and keep a simple diary/calendar. Researchers will compare the group with ingestion of Falcarinol (FaOH) / Falcarindiol (FaDOH) rich carrot juice versus the group consuming placebo juice, to see if the polyacetylenes significantly reduces neoplastic transformation and growth in high-risk patients.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Polyp prophylactic properties of polyacetylenes from carrots in patients with previous polypectomy-Px7 The study protocol of a multicentre binational randomised controlled trial.
Agache A, Deding U, Kaalby L, Kobaek-Larsen M, et al · · 2025 · PMID 41314836 · DOI 10.1136/bmjopen-2024-095376
Verify or expand the search:
- PubMed search for NCT06335420
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06335420 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Odense University Hospital
- Last refreshed: 20 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06335420.
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