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NCT06335420: Px7

Prophylactic Properties of Carrot Juice in Patients With High-Risk Colorectal Polyps

Recruiting now NA Last updated 20 November 2025
What this trial tests

NA trial testing Carrot juice from Yellowstone carrots cultivars in Colorectal Cancer Prevention in 400 participants. Currently enrolling.

Timeline
20 June 2024
Primary endpoint
1 June 2027
1 December 2027

Quick facts

Lead sponsorOdense University Hospital
PhaseNA
StatusRecruiting now
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingquadruple
Primary purposeprevention
Enrollment400
Start date20 June 2024
Primary completion1 June 2027
Estimated completion1 December 2027
Sites1 location across Denmark

Drugs / interventions tested

Conditions studied

Sponsor

Odense University Hospital

Who can join

18 and older, any sex, with Colorectal Cancer Prevention. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this prospective randomized double-blinded bi-national study is to test the prophylactic effect of polyacetylenes from carrots on the population of patients who had a resection of high-risk adenomas of the large bowel. The main question it aims to answer is: Will carrot juice rich in polyacetylenes inhibit neoplastic transformation and growth in high-risk humans? Participants will have to drink 100 ml of juice daily after the adenoma resection for 1 year and keep a simple diary/calendar. Researchers will compare the group with ingestion of Falcarinol (FaOH) / Falcarindiol (FaDOH) rich carrot juice versus the group consuming placebo juice, to see if the polyacetylenes significantly reduces neoplastic transformation and growth in high-risk patients.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Polyp prophylactic properties of polyacetylenes from carrots in patients with previous polypectomy-Px7 The study protocol of a multicentre binational randomised controlled trial.
    Agache A, Deding U, Kaalby L, Kobaek-Larsen M, et al · · 2025 · PMID 41314836 · DOI 10.1136/bmjopen-2024-095376

Verify or expand the search:

Other recruiting trials for Colorectal Cancer Prevention

Currently open trials in the same condition.

Other Odense University Hospital trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06335420.

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