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NCT06335108
Postoperative Pain After Breast Surgery Under Tumescent Local Anaesthesia Versus General Anaesthesia ( TLA-001 )
trial testing General Anaesthesia in Breast Carcinoma in 349 participants. Completed in 30 June 2025.
30 June 2025
Quick facts
| Lead sponsor | University Hospital Tuebingen |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 349 |
| Start date | 5 December 2022 |
| Primary completion | 30 June 2025 |
| Estimated completion | 30 June 2025 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- General Anaesthesia
- Local tumescent anaesthesia
Conditions studied
- Breast Carcinoma — all drugs for Breast Carcinoma →
- Breast Carcinoma in Situ — all drugs for Breast Carcinoma in Situ →
Sponsor
University Hospital Tuebingen
Who can join
18 and older, female only, with Breast Carcinoma or Breast Carcinoma in Situ. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The present study aims to investigate the impact of Tumescent Local Anesthesia (TLA) on pain perception following surgeries typical for breast cancer. Previous research has already confirmed the feasibility of conducting operations in TLA for benign breast conditions. In contrast to general anesthesia, Tumescent Local Anesthesia involves local anesthesia of the surgical site, allowing patients to remain awake during the procedure and eliminating the risks associated with general anesthesia. Additionally, if needed, sedatives or further anesthesia can be administered through the vein. Building upon the successful applications of TLA in benign breast surgeries, this follow-up study at the Department of Women's Health focuses on enhancing surgical techniques, pain management, and postoperative care for breast cancer-related procedures. Simultaneously, our goal is to gather scientific data regarding the application of this technique. This research contributes to the continuous advancement of medical practices in the field of breast surgery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06335108
- Europe PMC full search
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Related trials
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Other recruiting trials for Breast Carcinoma
Currently open trials in the same condition.
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Other University Hospital Tuebingen trials
Trials by the same sponsor.
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- NCT07276503 — Verification of a New Predictive Delirium Score in Adults With Elective Cardiac Valve or Bypass Surgery With Perioperati · not yet recruiting
- NCT07411365 — Dual-task Cognitive-motor Telerehabilitation in Persons With PD-MCI · NA · not yet recruiting
- NCT06953791 — Comparison of Quality of Life During a Flare of Crohn's Disease Treated With Prednisolone or aCDED With PEN in Adult Pat · Phase 2 · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06335108 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital Tuebingen
- Last refreshed: 26 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06335108.
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