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NCT06335017
The Effect of Combining Balloon Catheter With Castor Oil Ingestion for Cervical Ripening on Time to Delivery Among Multiparous Women.
NA trial testing Induction of labor in Induction of Labor in 216 participants. Currently enrolling.
1 November 2026
Quick facts
| Lead sponsor | Holy Family Hospital, Nazareth, Israel |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | other |
| Enrollment | 216 |
| Start date | 10 April 2024 |
| Primary completion | 1 November 2026 |
| Estimated completion | 1 December 2026 |
| Sites | 1 location across Israel |
Drugs / interventions tested
- Induction of labor — full drug profile →
Conditions studied
- Induction of Labor — all drugs for Induction of Labor →
Sponsor
Holy Family Hospital, Nazareth, Israel
Who can join
Adults 18 to 60, female only, with Induction of Labor. Healthy volunteers can join.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
time to delivery
Time frame: 48 hours
Time from catheter insertion to vaginal delivery
Sponsor's own description
The goal of this randomized controlled trial is to examine the efficacy of combining castor oil ingestion with extra-amniotic single balloon catheter for cervical ripening on time from induction to delivery in multiparous women. The main question it aims to answer are: Does the addition of the use of castor oil to extra-amniotic single balloon reduce the time until birth? Does the addition of the castor oil affect other perinatal outcomes during childbirth? Are the side effects of the castor tolerated by the mothers? Participants will be randomly divided into 2 groups: the study group will drink a mixture of 60 ml of castor oil mixed with 140 ml of orange juice. Thirty minutes later, extra-amniotic single balloon catheter will be inserted above the internal cervical os and filled with 60 mL of normal saline. In the control group, the catheter will be inserted into cervical canal without ingestion of castor oil.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06335017
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Induction of labor
Trials testing the same drug.
- NCT06325007 — Castor Oil Ingestion and Balloon Catheter for Labor Induction in Nulliparous · NA · recruiting
Other recruiting trials for Induction of Labor
Currently open trials in the same condition.
- NCT06803992 — Induction of Labor - Comparison Propess With Prostaglandin E2 Vaginal Gel and Balloon Catheter · Phase 4 · recruiting
Other Holy Family Hospital, Nazareth, Israel trials
Trials by the same sponsor.
- NCT06963047 — Evaluation of Blood Loss After Cesarean Delivery Via US Compared to Standard Care · NA · recruiting
- NCT06953141 — Ultrasound for Assessment of Intra-Abdominal Blood Loss After Gynecological Surgery · recruiting
- NCT06325007 — Castor Oil Ingestion and Balloon Catheter for Labor Induction in Nulliparous · NA · recruiting
- NCT05481853 — One Anastomosis Gastric Bypass for Severe Obesity in 6,722 Patients: Early Outcomes From the Assuta Surgery Registry · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06335017 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Holy Family Hospital, Nazareth, Israel
- Last refreshed: 7 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06335017.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing