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NCT06334471: WGS SIT

Whole Genome Sequencing in Breast Cancer

Recruiting now Last updated 3 April 2024
What this trial tests

trial testing no intervention needed in Breast Cancer in 1,200 participants. Currently enrolling.

Timeline
2 August 2022
Primary endpoint
2 August 2025
31 December 2030

Quick facts

Lead sponsorInocras Korea Inc.
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment1,200
Start date2 August 2022
Primary completion2 August 2025
Estimated completion31 December 2030
Sites1 location across South Korea

Drugs / interventions tested

Conditions studied

Sponsor

Inocras Korea Inc.

Who can join

19 and older, any sex, with Breast Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study aims to conduct whole genome sequencing in breast cancer patients to elucidate individual genetic characteristics and their correlation with breast cancer subtypes. The primary objective is to establish new treatment guidelines aligned with the paradigm shift in precision medicine. The study will include both prospective and retrospective cohorts totaling 1200 participants. Prospective participants must provide consent and be eligible for tissue collection, while retrospective participants must have histologically confirmed breast cancer and available tissue samples from Samsung Medical Center Biobank. The study period spans 3 years for subject enrollment and 5 years for follow-up observations, with an expected completion date of December 31, 2030.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Whole-genome landscapes of 1,364 breast cancers.
    Kim R, Yu J, Lim J, Oh BB, et al · · 2026 · cited 1× · PMID 41339552 · DOI 10.1038/s41586-025-09812-3

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