NCT06329102: RCC

Right Colectomy for Colon Cancer Database (RCC). Surgical Technique, Route of Access and Quality of the Specimen

Recruiting now Last updated 15 September 2025

What this trial tests

trial testing Surgical access in Right Sided Colon Cancer in 1,000 participants. Currently enrolling.

Timeline

1 January 2021

Primary endpoint
1 September 2030

1 September 2030

Quick facts

Lead sponsor	Haukeland University Hospital
Status	Recruiting now
Study type	OBSERVATIONAL
Enrollment	1,000
Start date	1 January 2021
Primary completion	1 September 2030
Estimated completion	1 September 2030
Sites	1 location across Norway

Drugs / interventions tested

• Surgical access

Conditions studied

• Right Sided Colon Cancer — all drugs for Right Sided Colon Cancer →
• Right Colectomy — all drugs for Right Colectomy →
• Lymphadenectomy — all drugs for Lymphadenectomy →

Sponsor

Haukeland University Hospital

Who can join

Adults 18 to 99, any sex, with Right Sided Colon Cancer or Right Colectomy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Aim of the project is to surveil results after extended lymphadenectomy for right sided colon resection for cancer with different operative techniques. Patients operated for right sided colon cancer will be involved. There are different operative methods used in terms of extend of lymphadenectomy and access (open, laparoscopic and robotic assisted) that are already implemented. The Norwegian standard operation contains less extended lymph node dissection. Patients operated by the standard method will serve as control group. Choice of access and extend of lymph node dissection in Norway is dependant on the surgeon and hospital. At Haukeland University Hospital extend and access of surgery are determined by a multidisciplinary team meeting. More radical surgery might result in more complications and the benefit for the patients in terms of oncological result and survival is uncertain. At Haukeland University Hospital, extended lymphadenectomy has been mostly performed by open surgery. During the study phase we will introduce extended lymphadenectomy by laparoscopy and robotassisted surgery. Hypothesis is that more radical surgery performed by minimal invasive surgery will result in equal or better oncological results, and less complications, shorter hospital stay and better quality of life. As method we choose a prospective observational study. All eligible patients with adenocarcinoma of the right colon without another ongoing oncological treatment for other cancers will be included. Patientdata will be prospectively registered in a web-based database. Aim of the study will be to define the optimal extend of lymphadenectomy to achieve the best oncological result. In addition, we will analyse the results dependent on the surgical access (open, laparoscopic or robotic). The assumed difference between the operative methods is small. Therefore, the study is designed and approved as a multicenter registration in order to achieve the necessary statistical power.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Proposal of a new visual analogue scale to describe the extent of lymphadenectomy in right-sided colectomy for cancer-a prospective observational study.
   Pfeffer F, Kalgraff P, Lygre KB, Nedrebø BS, et al · · 2025 · PMID 40892141 · DOI 10.1007/s10151-025-03182-8
2. Proposal of a new visual analogue scale to describe the extent of lymphadenectomy in right-sided colectomy for cancer – A prospective observational study
   Pfeffer F, Kalgraff P, Lygre KB, Nedrebo BS, et al · · 2025 · DOI 10.21203/rs.3.rs-6446786/v1