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NCT06328985
Intermittent Oro-esophageal Tube Feeding in Traumatic Brain Injury Patients
NA trial testing Rehabilitation therapy in Traumatic Brain Injury in 98 participants. Completed in 30 October 2025.
16 October 2025
Quick facts
| Lead sponsor | Copka Sonpashan |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | supportive care |
| Enrollment | 98 |
| Start date | 30 March 2024 |
| Primary completion | 16 October 2025 |
| Estimated completion | 30 October 2025 |
| Sites | 2 locations across China |
Drugs / interventions tested
- Rehabilitation therapy
- Intermittent Oro-esophageal Tube Feeding
- Nasogastric tube feeding
Conditions studied
- Traumatic Brain Injury — all drugs for Traumatic Brain Injury →
Sponsor
Copka Sonpashan
Who can join
18 and older, any sex, with Traumatic Brain Injury. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This was a multicenter randomized controlled study of 98 severe Traumatic Brain Injury patients with tracheostomy. Patients enrolled were divided randomly into the observation group with Intermittent Oro-esophageal Tube Feeding or the control group with Nasogastric tube feeding for enteral nutrition support, respectively. Nutritional status, complications, decannulation of tracheostomy tubes and level of consciousness on day 1 and day 28 were recorded and compared.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Oro-esophageal feeding for tracheostomized patients with severe traumatic brain injury: a randomized controlled trial.
Lv D, Liu H, Zhao J, Liu Y, et al · · 2026 · PMID 42261876 · DOI 10.1080/07853890.2026.2685913
Verify or expand the search:
- PubMed search for NCT06328985
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Rehabilitation therapy
Trials testing the same drug.
- NCT07318714 — A Study of ASP2246 for People Who Have Movement Problems Caused by Brain Injury After a Stroke · Phase 1, PHASE2 · recruiting
- NCT06261281 — Effect of Intermittent Oro-esophageal Tube Feeding on Severe Traumatic Brain Injury Patient · NA · withdrawn
- NCT06215742 — Clinical Effect of Stellate Ganglion Block on Gastroesophageal Reflux Disease · NA · withdrawn
- NCT06228170 — Efficacy of Stellate Ganglion Block in Traumatic Brain Injury Patients · NA · withdrawn
- NCT06215794 — Effect of Glossopharyngeal Nerve Block on Pharyngeal Dysphagia Induced by Gastroesophageal Reflux Disease · NA · withdrawn
Other recruiting trials for Traumatic Brain Injury
Currently open trials in the same condition.
- NCT07176936 — Improving Speech in Noise Using Noninvasive Stimulation · NA · recruiting
- NCT07473505 — Integrative Bilateral Cervical Sympathetic Blocks for Trauma-Related Symptoms in Special Operations Veterans: A Prospect · recruiting
- NCT07455136 — A Study to Develop a Blood-based Test for Aiding the Diagnosis/Prognosis of Traumatic Brain Injury in Adults and for Mon · recruiting
- NCT07404761 — Safety and Effectiveness of Spatial StimelMD (SSMD) in Subjects With Upper Limb Neuromotor Impairments · NA · recruiting
- NCT07230002 — Effects of Moderate/Severe Traumatic Brain Injury in the Subacute or Chronic Phase on Locomotor Strategies Involved in N · NA · recruiting
Other Copka Sonpashan trials
Trials by the same sponsor.
- NCT06328894 — Effect of Different Feeding Modes on Psychological Condition and Experience in Stroke Patients · NA · completed
- NCT06328231 — The Impact of Swallowing Intervention for Elderly Community Dwellers · NA · completed
- NCT06319534 — Stellate Ganglion Block in Bulbar Palsy · NA · completed
- NCT06335316 — Effect of Stellate Nerve Block in Dysphagia · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06328985 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Copka Sonpashan
- Last refreshed: 28 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06328985.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing