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NCT06328530
Itch Sensation Induced by Simultaneous Application of Pruritogens (Spatial Summation)
NA trial testing Cowhage in Histamine in 24 participants. Currently enrolling.
31 December 2025
Quick facts
| Lead sponsor | Aalborg University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | single group |
| Masking | single |
| Primary purpose | basic science |
| Enrollment | 24 |
| Start date | 1 April 2024 |
| Primary completion | 31 December 2025 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Cowhage
- Histamine (HISTAMINE) — full drug profile →
Conditions studied
Sponsor
Aalborg University
Who can join
Adults 18 to 60, any sex, with Histamine or Cowhage. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In This experiment, the investigators would like to design a new itch model based on the spatial summation of pruritic stimuli. The hypothesis behind this study (spatial summation) is that two simultaneous applications of pruritogens will result in higher itch sensation compared with a single application of pruritogen.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06328530
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Related trials
Other trials of Cowhage
Trials testing the same drug.
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- NCT07017231 — Role of Interleukin-13 Pathways on Pain and Itch Sensitivity ( IL-13 ) · NA · active not recruiting
- NCT06503510 — Role of Interleukin-13 Pathways on Pain and Itch Sensitivity · NA · recruiting
- NCT06328543 — Itch Sensation Induced by Multiple Applications of Pruritogens (temporal Summation) · NA · recruiting
Other recruiting trials for Histamine
Currently open trials in the same condition.
- NCT06328543 — Itch Sensation Induced by Multiple Applications of Pruritogens (temporal Summation) · NA · recruiting
- NCT06340438 — Investigate the Relationship Between Catastrophizing and the Perception of Itch Intensity in Healthy Individuals · NA · recruiting
- NCT06081946 — Investigation of the Effects of Sleep Fragmentation on Itch and Pain Sensitivity · NA · recruiting
- NCT06081998 — Investigation of the Effects of Sleep Deprivation on Itch and Pain Sensitivity · NA · recruiting
- NCT06152497 — The Role of Histamine in Muscle Protein Synthesis Following Resistance Training · NA · recruiting
Other Aalborg University trials
Trials by the same sponsor.
- NCT07580989 — Network Effects of Left M1 rTMS: A TMS-EEG Study · NA · recruiting
- NCT07395882 — A New Model to Induce Itch and Inflammation · NA · not yet recruiting
- NCT07395869 — Off-set Analgesia Induced by Cold Temperature · NA · not yet recruiting
- NCT07266103 — Mechanistic Study of Personalized rTMS in Chronic Pain · NA · not yet recruiting
- NCT07373392 — Effects of LP-LDL® on Lipid Metabolism, Glycemic Control, Inflammatory Markers, and Cognitive Function in Individuals Wi · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06328530 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Aalborg University
- Last refreshed: 6 May 2024
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