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NCT06328114

Accelerating TMS for Cervical Dystonia

ENROLLING BY INVITATION NA Last updated 2 April 2026
What this trial tests

NA trial testing Transcranial Magnetic Stimulation (TMS) in Isolated Cervical Dystonia in 50 participants. Enrolling by invitation.

Timeline
17 December 2024
Primary endpoint
1 July 2029
1 July 2029

Quick facts

Lead sponsorDuke University
PhaseNA
StatusENROLLING BY INVITATION
Study typeINTERVENTIONAL
Allocationrandomized
Designcrossover
Maskingtriple
Primary purposetreatment
Enrollment50
Start date17 December 2024
Primary completion1 July 2029
Estimated completion1 July 2029
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

Duke University

Who can join

18 and older, any sex, with Isolated Cervical Dystonia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study aims to investigate the impact of accelerated transcranial magnetic stimulation (TMS) on brain function and behavior in patients with focal cervical dystonia. Previous research demonstrated that individualized TMS improved writing behavior in focal hand dystonia after one session. In this study, we aim to expand the application on TMS on focal cervical dystonia. The current study administers four TMS sessions in a day. The research involves 9 in-person visits. The effect of TMS will be assessed using functional MRI brain scans and behavioral measurements. The risk of TMS includes seizures; the potential risk of seizures from TMS is mitigated through careful screening, adhering to safety guidelines. The study's main benefit is enhancing dystonic behavior and deepening the understanding of brain changes caused by TMS in cervical dystonia, paving the way for further advancements in clinical therapy for this condition.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other trials of Transcranial Magnetic Stimulation (TMS)

Trials testing the same drug.

Other recruiting trials for Isolated Cervical Dystonia

Currently open trials in the same condition.

Other Duke University trials

Trials by the same sponsor.

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Data sources for this page

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